Variant ID: 1-55512259-C-G

NM_174936.3(PCSK9):c.463C>G;(p.Pro155Ala)

This variant was identified in 2 publications




Publications:


The proprotein convertase subtilisin/kexin type 9 (PCSK9) active site and cleavage sequence differentially regulate protein secretion from proteolysis.

The Journal Of Biological Chemistry
JS Chorba, KM Shokat
Publication Date: 2014-10-17

Variant appearance in text: PCSK9: P155A
PMID: 25210046
View BVdb publication page



Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.

The Journal Of Biological Chemistry
Y Zhang, C Eigenbrot, L Zhou, S Shia, W Li, C Quan, J Tom, P Moran, P Di Lello, NJ Skelton, M Kong-Beltran, A Peterson, D Kirchhofer
Publication Date: 2014-01-10

Variant appearance in text: PCSK9: P155A
PMID: 24225950
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000302118.5 c.463C>G p.Pro155Ala missense_variant 3/12 -
ENST00000452118.2 c.463C>G p.Pro155Ala missense_variant 3/6 -
ENST00000543384.1 c.-77-5692C>G - intron_variant - 1/9
NM_174936.4 c.463C>G p.Pro155Ala missense_variant 3/12 -
NR_110451.1 n.183-5692C>G - intron_variant,non_coding_transcript_variant - 1/9