POLE c.1635G>T ;(p.E545D)

Variant ID: 12-133249264-C-A

NM_006231.2(POLE):c.1635G>T;(p.E545D)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: POLE: E545D
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



The NRF2 transcriptional target NQO1 has low mRNA levels in TP53-mutated endometrial carcinomas.

Plos One
Beinse, Guillaume G; Just, Pierre-Alexandre PA; Rance, Bastien B; Izac, Brigitte B; Letourneur, Franck F; Saidu, Nathaniel Edward Bennett NEB; Chouzenoux, Sandrine S; Nicco, Carole C; Goldwasser, François F; Pasmant, Eric E; Batteux, Frederic F; Borghese, Bruno B; Alexandre, Jérôme J; Leroy, Karen K
Publication Date: 2019

Variant appearance in text: POLE: Glu545Asp
PubMed Link: 30908539
Variant Present in the following documents:
  • pone.0214416.s013.xlsx, sheet 1
View BVdb publication page