Publications:

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Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology

Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2023-04-28

Variant appearance in text: KRAS: A59G

PubMed Link: 37207265

Variant Present in the following documents:

• media-1.pdf

View BVdb publication page

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Impacts of Mutations in the P-Loop on Conformational Alterations of KRAS Investigated with Gaussian Accelerated Molecular Dynamics Simulations.

Molecules (Basel, Switzerland)

Shi, Shuhua S; Zheng, Linqi L; Ren, Yonglian Y; Wang, Ziyu Z

Publication Date: 2023-03-23

Variant appearance in text: KRAS: A59G

PubMed Link: 37049650

Variant Present in the following documents:

• molecules-28-02886.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: KRAS: A59G

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3

View BVdb publication page

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: KRAS: A59G

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

View BVdb publication page

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KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences

Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN

Publication Date: 2023-03-02

Variant appearance in text: KRAS: A59G

PubMed Link: 36902296

Variant Present in the following documents:

• Main text
• ijms-24-04868.pdf

View BVdb publication page

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In Silico Evaluation of the Thr58-Associated Conserved Water with KRAS Switch-II Pocket Binders.

Journal Of Chemical Information And Modeling

Leini, Renne R; Pantsar, Tatu T

Publication Date: 2023-02-28

Variant appearance in text: KRAS: A59G

PubMed Link: 36854010

Variant Present in the following documents:

• ci2c01479_si_002.xlsx, sheet 1

View BVdb publication page

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Novel mutant KRAS addiction signature predicts response to the combination of ERBB and MEK inhibitors in lung and pancreatic cancers.

Iscience

Tyc, Katarzyna M KM; Kazi, Aslamuzzaman A; Ranjan, Alok A; Wang, Rui R; Sebti, Said M SM

Publication Date: 2023-03-17

Variant appearance in text: KRAS: A59G

PubMed Link: 36852277

Variant Present in the following documents:

• mmc2.xlsx, sheet 2

View BVdb publication page

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Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery

Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J

Publication Date: 2023-02-08

Variant appearance in text: KRAS: A59G

PubMed Link: 36751942

Variant Present in the following documents:

• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 1
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 4

View BVdb publication page

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Advantages and Limitations of Monitoring Circulating Tumor DNA Levels to Predict the Prognosis of Patients Diagnosed With Gastric Cancer.

Biomarker Insights

He, Wan W; Yang, Jingxin J; Sun, Xiao X; Jiang, Shunda S; Jiang, Jinchan J; Liu, Ming M; Mu, Tianhao T; Li, Yingmei Y; Zhang, Xiaoni X; Duan, Jingxian J; Xu, Ruilian R

Publication Date: 2022

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 36533271

Variant Present in the following documents:

• sj-xlsx-2-bmi-10.1177_11772719221141525.xlsx, sheet 1

View BVdb publication page

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: KRAS: A59G

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KRAS: A59G

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 36344948

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10235.pdf

View BVdb publication page

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Targeting RAS mutants in malignancies: successes, failures, and reasons for hope.

Cancer Communications (London, England)

Yang, Hang H; Zhou, Xinyi X; Fu, Dongliang D; Le, Chenqin C; Wang, Jiafeng J; Zhou, Quan Q; Liu, Xiangrui X; Yuan, Ying Y; Ding, Kefeng K; Xiao, Qian Q

Publication Date: 2022-10-31

Variant appearance in text: KRAS: A59G

PubMed Link: 36316602

Variant Present in the following documents:

• Main text
• CAC2-43-42.pdf

View BVdb publication page

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Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology

Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W

Publication Date: 2022

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 36238300

Variant Present in the following documents:

• Table_1.xlsx, sheet 4

View BVdb publication page

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: KRAS: A59G

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1

View BVdb publication page

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EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine

Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W

Publication Date: 2022-09-19

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 36123678

Variant Present in the following documents:

• 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cancers

Cekani, Elona E; Epistolio, Samantha S; Dazio, Giulia G; Cefalì, Marco M; Wannesson, Luciano L; Frattini, Milo M; Froesch, Patrizia P

Publication Date: 2022-08-24

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 36077640

Variant Present in the following documents:

• cancers-14-04103.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Is Cell-Free DNA Testing in Pancreatic Ductal Adenocarcinoma Ready for Prime Time?

Cancers

Sheel, Ankur A; Addison, Sarah S; Nuguru, Surya Pratik SP; Manne, Ashish A

Publication Date: 2022-07-15

Variant appearance in text: KRAS: A59G

PubMed Link: 35884515

Variant Present in the following documents:

• cancers-14-03453.pdf

View BVdb publication page

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Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Durinikova, Erika E; Reilly, Nicole M NM; Buzo, Kristi K; Mariella, Elisa E; Chilà, Rosaria R; Lorenzato, Annalisa A; Dias, João M L JML; Grasso, Gaia G; Pisati, Federica F; Lamba, Simona S; Corti, Giorgio G; Degasperi, Andrea A; Cancelliere, Carlotta C; Mauri, Gianluca G; Andrei, Pietro P; Linnebacher, Michael M; Marsoni, Silvia S; Siena, Salvatore S; Sartore-Bianchi, Andrea A; Nik-Zainal, Serena S; Di Nicolantonio, Federica F; Bardelli, Alberto A; Arena, Sabrina S

Publication Date: 2022-09-01

Variant appearance in text: KRAS: A59G

PubMed Link: 35881546

Variant Present in the following documents:

• EMS151756-supplement-Table_S1.xlsx, sheet 1

View BVdb publication page

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The treatment of advanced non-small cell lung cancer harboring KRAS mutation: a new class of drugs for an old target-a narrative review.

Translational Lung Cancer Research

Spagnuolo, Alessia A; Maione, Paolo P; Gridelli, Cesare C

Publication Date: 2022-06

Variant appearance in text: KRAS: A59G

PubMed Link: 35832439

Variant Present in the following documents:

• Main text
• tlcr-11-06-1199.pdf

View BVdb publication page

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The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Nature Communications

Vo, Josh N JN; Wu, Yi-Mi YM; Mishler, Jeanmarie J; Hall, Sarah S; Mannan, Rahul R; Wang, Lisha L; Ning, Yu Y; Zhou, Jin J; Hopkins, Alexander C AC; Estill, James C JC; Chan, Wallace K B WKB; Yesil, Jennifer J; Cao, Xuhong X; Rao, Arvind A; Tsodikov, Alexander A; Talpaz, Moshe M; Cole, Craig E CE; Ye, Jing C JC; , ; Bergsagel, P Leif PL; Auclair, Daniel D; Cho, Hearn Jay HJ; Robinson, Dan R DR; Chinnaiyan, Arul M AM

Publication Date: 2022-06-29

Variant appearance in text: KRAS: 176C>G; Ala59Gly

PubMed Link: 35768438

Variant Present in the following documents:

• 41467_2022_31430_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: KRAS: A59G

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Delineating the RAS Conformational Landscape.

Cancer Research

Parker, Mitchell I MI; Meyer, Joshua E JE; Golemis, Erica A EA; Dunbrack, Roland L RL

Publication Date: 2022-07-05

Variant appearance in text: KRAS: A59G

PubMed Link: 35536216

Variant Present in the following documents:

• 2485.pdf
• can-22-0804_supplementary_datasets_s1-s4_suppsds1-sds4.xlsx, sheet 1

View BVdb publication page

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Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics

Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R

Publication Date: 2022-04-25

Variant appearance in text: KRAS: 176C>G

PubMed Link: 35468810

Variant Present in the following documents:

• 12920_2022_1235_MOESM3_ESM.xlsx, sheet 1
• 12920_2022_1235_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Autopromotion of K-Ras4B Feedback Activation Through an SOS-Mediated Long-Range Allosteric Effect.

Frontiers In Molecular Biosciences

He, Xuan X; Du, Kui K; Wang, Yuanhao Y; Fan, Jigang J; Li, Mingyu M; Ni, Duan D; Lu, Shaoyong S; Bian, Xiaolan X; Liu, Yaqin Y

Publication Date: 2022

Variant appearance in text: K-Ras4B: A59G

PubMed Link: 35463958

Variant Present in the following documents:

• Main text

View BVdb publication page

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Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.

International Journal Of Molecular Sciences

Calabrese, Fiorella F; Pezzuto, Federica F; Lunardi, Francesca F; Fortarezza, Francesco F; Tzorakoleftheraki, Sofia-Eleni SE; Resi, Maria Vittoria MV; Tiné, Mariaenrica M; Pasello, Giulia G; Hofman, Paul P

Publication Date: 2022-04-09

Variant appearance in text: KRAS: A59G

PubMed Link: 35456982

Variant Present in the following documents:

• Main text
• ijms-23-04164.pdf

View BVdb publication page

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Daily Practice Assessment of KRAS Status in NSCLC Patients: A New Challenge for the Thoracic Pathologist Is Right around the Corner.

Cancers

Bontoux, Christophe C; Hofman, Véronique V; Brest, Patrick P; Ilié, Marius M; Mograbi, Baharia B; Hofman, Paul P

Publication Date: 2022-03-23

Variant appearance in text: KRAS: A59G

PubMed Link: 35406400

Variant Present in the following documents:

• cancers-14-01628.pdf

View BVdb publication page

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KRAS Mutation in Rare Tumors: A Landscape Analysis of 3453 Chinese Patients.

Frontiers In Molecular Biosciences

Wang, Shuhang S; Li, Qin Q; Ma, Peiwen P; Fang, Yuan Y; Yu, Yue Y; Jiang, Ning N; Miao, Huilei H; Tang, Qiyu Q; Yang, Yuqi Y; Xing, Shujun S; Chen, Rongrong R; Yi, Xin X; Li, Ning N

Publication Date: 2022

Variant appearance in text: KRAS: A59G

PubMed Link: 35359599

Variant Present in the following documents:

• Main text
• fmolb-09-831382.pdf

View BVdb publication page

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

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The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology

Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q

Publication Date: 2021

Variant appearance in text: KRAS: A59G

PubMed Link: 35273907

Variant Present in the following documents:

• Table_7.xlsx, sheet 1

View BVdb publication page

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Targeting KRAS Mutant in Non-Small Cell Lung Cancer: Novel Insights Into Therapeutic Strategies.

Frontiers In Oncology

Désage, Anne-Laure AL; Léonce, Camille C; Swalduz, Aurélie A; Ortiz-Cuaran, Sandra S

Publication Date: 2022

Variant appearance in text: KRAS: A59G

PubMed Link: 35251972

Variant Present in the following documents:

• Main text
• fonc-12-796832.pdf

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: KRAS: 176C>G; Ala59Gly

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data3.xlsx, sheet 1
• Supplementary_Data2.xlsx, sheet 1

View BVdb publication page

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Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.

Cell Reports

Khan, Imran I; Koide, Akiko A; Zuberi, Mariyam M; Ketavarapu, Gayatri G; Denbaum, Eric E; Teng, Kai Wen KW; Rhett, J Matthew JM; Spencer-Smith, Russell R; Hobbs, G Aaron GA; Camp, Ernest Ramsay ER; Koide, Shohei S; O'Bryan, John P JP

Publication Date: 2022-02-08

Variant appearance in text: KRAS: A59G

PubMed Link: 35139380

Variant Present in the following documents:

• nihms-1778820.pdf

View BVdb publication page

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Tumor irradiation may facilitate the detection of tumor-specific mutations in plasma.

World Journal Of Clinical Oncology

Kuligina, Ekaterina E; Moiseyenko, Fedor F; Belukhin, Sergey S; Stepanova, Ekaterina E; Zakharova, Maria M; Chernobrivtseva, Vera V; Aliev, Ikram I; Sharabura, Tatiana T; Moiseyenko, Vladimir V; Aleksakhina, Svetlana S; Laidus, Tatiana T; Martianov, Aleksandr A; Kholmatov, Maksim M; Whitehead, Aldon A; Yanus, Grigoriy G; Imyanitov, Evgeny E

Publication Date: 2021-12-24

Variant appearance in text: KRAS: A59G

PubMed Link: 35070740

Variant Present in the following documents:

• Main text

View BVdb publication page

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Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.

Chemical Science

Lim, Shuhui S; Boyer, Nicolas N; Boo, Nicole N; Huang, Chunhui C; Venkatachalam, Gireedhar G; Angela Juang, Yu-Chi YC; Garrigou, Michael M; Kaan, Hung Yi Kristal HYK; Duggal, Ruchia R; Peh, Khong Ming KM; Sadruddin, Ahmad A; Gopal, Pooja P; Yuen, Tsz Ying TY; Ng, Simon S; Kannan, Srinivasaraghavan S; Brown, Christopher J CJ; Verma, Chandra S CS; Orth, Peter P; Peier, Andrea A; Ge, Lan L; Yu, Xiang X; Bhatt, Bhavana B; Chen, Feifei F; Wang, Erjia E; Li, Nianyu Jason NJ; Gonzales, Raymond J RJ; Stoeck, Alexander A; Henry, Brian B; Sawyer, Tomi K TK; Lane, David P DP; Johannes, Charles W CW; Biswas, Kaustav K; Partridge, Anthony W AW

Publication Date: 2021-12-15

Variant appearance in text: KRAS: A59G

PubMed Link: 35024121

Variant Present in the following documents:

• Main text
• SC-012-D1SC05187C.pdf

View BVdb publication page

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Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001.

Blood Advances

Tran, Thai Hoa TH; Langlois, Sylvie S; Meloche, Caroline C; Caron, Maxime M; Saint-Onge, Pascal P; Rouette, Alexandre A; Bataille, Alain R AR; Jimenez-Cortes, Camille C; Sontag, Thomas T; Bittencourt, Henrique H; Laverdière, Caroline C; Lavallée, Vincent-Philippe VP; Leclerc, Jean-Marie JM; Cole, Peter D PD; Gennarini, Lisa M LM; Kahn, Justine M JM; Kelly, Kara M KM; Michon, Bruno B; Santiago, Raoul R; Stevenson, Kristen E KE; Welch, Jennifer J G JJG; Schroeder, Kaitlin M KM; Koch, Victoria V; Cellot, Sonia S; Silverman, Lewis B LB; Sinnett, Daniel D

Publication Date: 2022-02-22

Variant appearance in text: KRAS: A59G

PubMed Link: 34933343

Variant Present in the following documents:

• advancesADV2021005634-suppl1.xlsx, sheet 1
• advancesADV2021005634-suppl1.xlsx, sheet 3

View BVdb publication page

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Mutation analysis of a 10-gene panel for colorectal cancer in Huizhou, Guangdong Province of China.

The Journal Of International Medical Research

Li, Jun J; Sun, Aihua A; Zhong, Guofang G; He, Ying Y; Xiong, Hailin H; Yuan, Xia X

Publication Date: 2021-11

Variant appearance in text: KRAS: 176C>G

PubMed Link: 34851763

Variant Present in the following documents:

• 10.1177_03000605211061040.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KRAS: A59G

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Transition From Distinct Types of KRAS Mutation-Harboring Multifocal Lung Adenocarcinoma to Rhabdoid Tumor: A Longitudinal Follow-Up.

The American Journal Of Case Reports

Setoguchi, Kensuke K; Yanagi, Shigehisa S; Gi, Toshihiro T; Tsubouchi, Hironobu H; Uto, Kazuko K; Shigekusa, Takafumi T; Matsumoto, Nobuhiro N; Sato, Yuichiro Y; Nakazato, Masamitsu M

Publication Date: 2021-08-25

Variant appearance in text: KRAS: A59G

PubMed Link: 34432771

Variant Present in the following documents:

• Main text
• amjcaserep-22-e932452.pdf

View BVdb publication page

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Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: KRAS: A59G

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 12
• Table_1.xlsx, sheet 2
• Table_1.xlsx, sheet 31

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Structural impact of GTP binding on downstream KRAS signaling.

Chemical Science

Menyhárd, Dóra K DK; Pálfy, Gyula G; Orgován, Zoltán Z; Vida, István I; Keserű, György M GM; Perczel, András A

Publication Date: 2020-08-19

Variant appearance in text: KRAS: A59G

PubMed Link: 34094198

Variant Present in the following documents:

• SC-011-D0SC03441J-s001.pdf

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KRAS G12C Mutations in NSCLC: From Target to Resistance.

Cancers

Addeo, Alfredo A; Banna, Giuseppe Luigi GL; Friedlaender, Alex A

Publication Date: 2021-05-21

Variant appearance in text: KRAS: A59G

PubMed Link: 34064232

Variant Present in the following documents:

• Main text
• cancers-13-02541.pdf

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Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools.

Scientific Reports

Garcia, Jessica J; Kamps-Hughes, Nick N; Geiguer, Florence F; Couraud, Sébastien S; Sarver, Brice B; Payen, Léa L; Ionescu-Zanetti, Cristian C

Publication Date: 2021-05-24

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 34031447

Variant Present in the following documents:

• 41598_2021_89592_MOESM1_ESM.xlsx, sheet 3

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Clinical and prognostic features of patients with detailed RAS/BRAF-mutant colorectal cancer in Japan.

Bmc Cancer

Ikoma, Tatsuki T; Shimokawa, Mototsugu M; Kotaka, Masahito M; Matsumoto, Toshihiko T; Nagai, Hiroki H; Boku, Shogen S; Shibata, Nobuhiro N; Yasui, Hisateru H; Satake, Hironaga H

Publication Date: 2021-05-07

Variant appearance in text: KRAS: A59G

PubMed Link: 33962575

Variant Present in the following documents:

• Main text

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: KRAS: A59G

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 5
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1

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TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer.

Npj Breast Cancer

da Silva, Edaise M EM; Selenica, Pier P; Vahdatinia, Mahsa M; Pareja, Fresia F; Da Cruz Paula, Arnaud A; Ferrando, Lorenzo L; Gazzo, Andrea M AM; Dopeso, Higinio H; Ross, Dara S DS; Bakhteri, Ariya A; Riaz, Nadeem N; Chandarlapaty, Sarat S; Razavi, Pedram P; Norton, Larry L; Wen, Hannah Y HY; Brogi, Edi E; Weigelt, Britta B; Zhang, Hong H; Reis-Filho, Jorge S JS

Publication Date: 2021-04-16

Variant appearance in text: KRAS: A59G

PubMed Link: 33863915

Variant Present in the following documents:

• Main text

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: KRAS: 176C>G; A59G

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

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Exquisitely Specific anti-KRAS Biodegraders Inform on the Cellular Prevalence of Nucleotide-Loaded States.

Acs Central Science

Lim, Shuhui S; Khoo, Regina R; Juang, Yu-Chi YC; Gopal, Pooja P; Zhang, Huibin H; Yeo, Constance C; Peh, Khong Ming KM; Teo, Jinkai J; Ng, Simon S; Henry, Brian B; Partridge, Anthony W AW

Publication Date: 2021-02-24

Variant appearance in text: KRAS: A59G

PubMed Link: 33655066

Variant Present in the following documents:

• Main text
• oc0c01337.pdf
• oc0c01337_si_001.pdf

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