Publications:

---

The mitochondrial Ca 2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation.

Biorxiv : The Preprint Server For Biology

García, Emily Fernández EF; Paudel, Usha U; Noji, Michael C MC; Bowman, Caitlyn E CE; Pitarresi, Jason R JR; Rustgi, Anil K AK; Wellen, Kathryn E KE; Arany, Zolt Z; Weissenrieder, Jillian S JS; Foskett, J Kevin JK

Publication Date: 2023-04-28

Variant appearance in text: CDK4: R24C

PubMed Link: 37163088

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases.

Pharmaceuticals (Basel, Switzerland)

Klein, Mark M

Publication Date: 2023-03-31

Variant appearance in text: CDK4: R24C

PubMed Link: 37111276

Variant Present in the following documents:

• Main text
• pharmaceuticals-16-00519.pdf

View BVdb publication page

---

Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors.

Frontiers In Immunology

Immisch, Lena L; Papafotiou, George G; Gallarín Delgado, Nerea N; Scheuplein, Vivian V; Paschen, Annette A; Blankenstein, Thomas T; Willimsky, Gerald G

Publication Date: 2023

Variant appearance in text: CDK4: R24C

PubMed Link: 36875127

Variant Present in the following documents:

• Main text
• fimmu-14-1119498.pdf

View BVdb publication page

---

Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: CDK4: 70C>T; Arg24Cys

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

---

Integrative proteomic characterization of adenocarcinoma of esophagogastric junction.

Nature Communications

Li, Shengli S; Yuan, Li L; Xu, Zhi-Yuan ZY; Xu, Jing-Li JL; Chen, Gui-Ping GP; Guan, Xiaoqing X; Pan, Guang-Zhao GZ; Hu, Can C; Dong, Jinyun J; Du, Yi-An YA; Yang, Li-Tao LT; Ni, Mao-Wei MW; Jiang, Rui-Bin RB; Zhu, Xiu X; Lv, Hang H; Xu, Han-Dong HD; Zhang, Sheng-Jie SJ; Qin, Jiang-Jiang JJ; Cheng, Xiang-Dong XD

Publication Date: 2023-02-11

Variant appearance in text: CDK4: 70C>T; Arg24Cys; rs11547328

PubMed Link: 36774361

Variant Present in the following documents:

• 41467_2023_36462_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Phytochemical Constituents and Derivatives of Cannabis sativa; Bridging the Gap in Melanoma Treatment.

International Journal Of Molecular Sciences

Schanknecht, Ellen E; Bachari, Ava A; Nassar, Nazim N; Piva, Terrence T; Mantri, Nitin N

Publication Date: 2023-01-03

Variant appearance in text: CDK4: R24C

PubMed Link: 36614303

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Immortalization of primary marmoset skin fibroblasts by CRISPR-Cas9-mediated gene targeting.

Animal Cells And Systems

Jeong, Yeon-Ju YJ; Cho, Jeongin J; Kwak, Jina J; Sung, Young Hoon YH; Kang, Byeong-Cheol BC

Publication Date: 2022

Variant appearance in text: CDK4: R24C

PubMed Link: 36605591

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Comprehensive transcriptome data to identify downstream genes of testosterone signalling in dermal papilla cells.

Scientific Data

Matsusaka, Himari H; Wu, Tao T; Furuya, Kai K; Yamada-Kato, Tomoe T; Bai, Lanlan L; Tomita, Hiroshi H; Sugano, Eriko E; Ozaki, Taku T; Kiyono, Tohru T; Okunishi, Isao I; Fukuda, Tomokazu T

Publication Date: 2022-11-29

Variant appearance in text: CDK4: R24C

PubMed Link: 36446804

Variant Present in the following documents:

• Main text
• 41597_2022_Article_1846.pdf

View BVdb publication page

---

Hyper-active RAS/MAPK introduces cancer-specific mitotic vulnerabilities.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Herman, Jacob A JA; Romain, Romario R RR; Hoellerbauer, Pia P; Shirnekhi, Hazheen K HK; King, David C DC; DeLuca, Keith F KF; Osborne Nishimura, Erin E; Paddison, Patrick J PJ; DeLuca, Jennifer G JG

Publication Date: 2022-10-11

Variant appearance in text: CDK4: R24C

PubMed Link: 36191188

Variant Present in the following documents:

• pnas.2208255119.sapp.pdf

View BVdb publication page

---

Cyclin-dependent kinase inhibitors in malignant hematopoiesis.

Frontiers In Oncology

Schirripa, Alessia A; Sexl, Veronika V; Kollmann, Karoline K

Publication Date: 2022

Variant appearance in text: CDK4: R24C

PubMed Link: 36033505

Variant Present in the following documents:

• Main text
• fonc-12-916682.pdf

View BVdb publication page

---

2-hydroxyethyl methacrylate-derived reactive oxygen species stimulate ATP release via TRPA1 in human dental pulp cells.

Scientific Reports

Orimoto, Ai A; Kitamura, Chiaki C; Ono, Kentaro K

Publication Date: 2022-07-19

Variant appearance in text: CDK4: R24C

PubMed Link: 35853988

Variant Present in the following documents:

• Main text
• 41598_2022_Article_16559.pdf

View BVdb publication page

---

Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: CDK4: 70C>T; R24C

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

---

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.

The Journal Of Clinical Investigation

Lee, Patrick C PC; Klaeger, Susan S; Le, Phuong M PM; Korthauer, Keegan K; Cheng, Jingwei J; Ananthapadmanabhan, Varsha V; Frost, Thomas C TC; Stevens, Jonathan D JD; Wong, Alan Yl AY; Iorgulescu, J Bryan JB; Tarren, Anna Y AY; Chea, Vipheaviny A VA; Carulli, Isabel P IP; Lemvigh, Camilla K CK; Pedersen, Christina B CB; Gartin, Ashley K AK; Sarkizova, Siranush S; Wright, Kyle T KT; Li, Letitia W LW; Nomburg, Jason J; Li, Shuqiang S; Huang, Teddy T; Liu, Xiaoxi X; Pomerance, Lucas L; Doherty, Laura M LM; Apffel, Annie M AM; Wallace, Luke J LJ; Rachimi, Suzanna S; Felt, Kristen D KD; Wolff, Jacquelyn O JO; Witten, Elizabeth E; Zhang, Wandi W; Neuberg, Donna D; Lane, William J WJ; Zhang, Guanglan G; Olsen, Lars R LR; Thakuria, Manisha M; Rodig, Scott J SJ; Clauser, Karl R KR; Starrett, Gabriel J GJ; Doench, John G JG; Buhrlage, Sara J SJ; Carr, Steven A SA; DeCaprio, James A JA; Wu, Catherine J CJ; Keskin, Derin B DB

Publication Date: 2022-07-01

Variant appearance in text: CDK4: 70C>T; Arg24Cys; rs11547328

PubMed Link: 35775490

Variant Present in the following documents:

• jci-132-151666-s195.xlsx, sheet 2

View BVdb publication page

---

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: CDK4: R24C

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

---

Shining Light on Protein Kinase Biomarkers with Fluorescent Peptide Biosensors.

Life (Basel, Switzerland)

Morris, May C MC

Publication Date: 2022-03-31

Variant appearance in text: CDK4: R24C

PubMed Link: 35455007

Variant Present in the following documents:

• Main text
• life-12-00516.pdf

View BVdb publication page

---

Genomic And Tumor Microenvironment Differences Between Cell Cycle Progression Pathway Altered/Non-Altered Patients With Lung Adenocarcinoma.

Frontiers In Oncology

Shan, Guangyao G; Bi, Guoshu G; Bian, Yunyi Y; Valeria, Besskaya B; Zeng, Dejun D; Zhang, Huan H; Yao, Guangyu G; Zhang, Yi Y; Fan, Hong H; Zhan, Cheng C

Publication Date: 2022

Variant appearance in text: CDK4: R24C

PubMed Link: 35296002

Variant Present in the following documents:

• Main text
• fonc-12-843528.pdf

View BVdb publication page

---

Development of human alveolar epithelial cell models to study distal lung biology and disease.

Iscience

Tran, Evelyn E; Shi, Tuo T; Li, Xiuwen X; Chowdhury, Adnan Y AY; Jiang, Du D; Liu, Yixin Y; Wang, Hongjun H; Yan, Chunli C; Wallace, William D WD; Lu, Rong R; Ryan, Amy L AL; Marconett, Crystal N CN; Zhou, Beiyun B; Borok, Zea Z; Offringa, Ite A IA

Publication Date: 2022-02-18

Variant appearance in text: CDK4: R24C

PubMed Link: 35169685

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Targeting GPCRs and Their Signaling as a Therapeutic Option in Melanoma.

Cancers

Raymond, Jérémy H JH; Aktary, Zackie Z; Larue, Lionel L; Delmas, Véronique V

Publication Date: 2022-01-29

Variant appearance in text: CDK4: R24C

PubMed Link: 35158973

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Targeting GPCRs and Their Signaling as a Therapeutic Option in Melanoma.

Cancers

Raymond, Jérémy H JH; Aktary, Zackie Z; Larue, Lionel L; Delmas, Véronique V

Publication Date: 2022-01-29

Variant appearance in text: CDK4: R24C

PubMed Link: 35158973

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Mapping oncogenic protein interactions for precision medicine.

International Journal Of Cancer

Sharifi Tabar, Mehdi M; Francis, Habib H; Yeo, Dannel D; Bailey, Charles G CG; Rasko, John E J JEJ

Publication Date: 2022-07-01

Variant appearance in text: CDK4: R24C

PubMed Link: 35113472

Variant Present in the following documents:

• Main text
• IJC-151-7.pdf

View BVdb publication page

---

A Notch inhibitor plus Resveratrol induced blockade of autophagy drives glioblastoma cell death by promoting a switch to apoptosis.

American Journal Of Cancer Research

Giordano, Francesca F; Montalto, Francesca Ida FI; Panno, Maria Luisa ML; Andò, Sebastiano S; Amicis, Francesca De F

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 35018234

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI).

Stem Cell Research & Therapy

Miyata, Shoko S; Saku, Noriaki N; Akiyama, Saeko S; Javaregowda, Palaksha Kanive PK; Ite, Kenta K; Takashima, Nagisa N; Toyoda, Masashi M; Yura, Kei K; Kimura, Tohru T; Nishina, Hiroshi H; Nakazawa, Atsuko A; Kasahara, Mureo M; Nonaka, Hidenori H; Kiyono, Tohru T; Umezawa, Akihiro A

Publication Date: 2022-01-10

Variant appearance in text: CDK4: R24C

PubMed Link: 35012658

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI).

Stem Cell Research & Therapy

Miyata, Shoko S; Saku, Noriaki N; Akiyama, Saeko S; Javaregowda, Palaksha Kanive PK; Ite, Kenta K; Takashima, Nagisa N; Toyoda, Masashi M; Yura, Kei K; Kimura, Tohru T; Nishina, Hiroshi H; Nakazawa, Atsuko A; Kasahara, Mureo M; Nonaka, Hidenori H; Kiyono, Tohru T; Umezawa, Akihiro A

Publication Date: 2022-01-10

Variant appearance in text: CDK4: R24C

PubMed Link: 35012658

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment.

Frontiers In Pharmacology

Thoma, Oana-Maria OM; Neurath, Markus F MF; Waldner, Maximilian J MJ

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 35002699

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Bmc Cancer

Karachaliou, Georgia Sofia GS; Alkallas, Rached R; Carroll, Sarah B SB; Caressi, Chongshan C; Zakria, Danny D; Patel, Nirali M NM; Trembath, Dimitri G DG; Ezzell, Jennifer A JA; Pegna, Guillaume J GJ; Googe, Paul B PB; Galeotti, Jonathan P JP; Ayvali, Fatih F; Collichio, Frances A FA; Lee, Carrie B CB; Ollila, David W DW; Gulley, Margaret L ML; Johnson, Douglas B DB; Kim, Kevin B KB; Watson, Ian R IR; Moschos, Stergios J SJ

Publication Date: 2022-01-05

Variant appearance in text: CDK4: R24C

PubMed Link: 34986841

Variant Present in the following documents:

• 12885_2021_8908_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Bmc Cancer

Karachaliou, Georgia Sofia GS; Alkallas, Rached R; Carroll, Sarah B SB; Caressi, Chongshan C; Zakria, Danny D; Patel, Nirali M NM; Trembath, Dimitri G DG; Ezzell, Jennifer A JA; Pegna, Guillaume J GJ; Googe, Paul B PB; Galeotti, Jonathan P JP; Ayvali, Fatih F; Collichio, Frances A FA; Lee, Carrie B CB; Ollila, David W DW; Gulley, Margaret L ML; Johnson, Douglas B DB; Kim, Kevin B KB; Watson, Ian R IR; Moschos, Stergios J SJ

Publication Date: 2022-01-05

Variant appearance in text: CDK4: R24C

PubMed Link: 34986841

Variant Present in the following documents:

• 12885_2021_8908_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Monoclonal antibodies to activated CDK4: use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27.

Cell Cycle (Georgetown, Tex.)

Coulonval, Katia K; Vercruysse, Vincent V; Paternot, Sabine S; Pita, Jaime M JM; Corman, Robert R; Raspé, Eric E; Roger, Pierre P PP

Publication Date: 2021-12-16

Variant appearance in text: CDK4: R24C

PubMed Link: 34913830

Variant Present in the following documents:

• KCCY_21_1984663.pdf

View BVdb publication page

---

Monoclonal antibodies to activated CDK4: use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27.

Cell Cycle (Georgetown, Tex.)

Coulonval, Katia K; Vercruysse, Vincent V; Paternot, Sabine S; Pita, Jaime M JM; Corman, Robert R; Raspé, Eric E; Roger, Pierre P PP

Publication Date: 2022-01

Variant appearance in text: CDK4: R24C

PubMed Link: 34913830

Variant Present in the following documents:

• KCCY_21_1984663.pdf

View BVdb publication page

---

Neoantigen-Reactive T Cells: The Driving Force behind Successful Melanoma Immunotherapy.

Cancers

Davis, Lindy L; Tarduno, Ashley A; Lu, Yong-Chen YC

Publication Date: 2021-12-01

Variant appearance in text: CDK4: R24C

PubMed Link: 34885172

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Neoantigen-Reactive T Cells: The Driving Force behind Successful Melanoma Immunotherapy.

Cancers

Davis, Lindy L; Tarduno, Ashley A; Lu, Yong-Chen YC

Publication Date: 2021-12-01

Variant appearance in text: CDK4: R24C

PubMed Link: 34885172

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Melanoma susceptibility: an update on genetic and epigenetic findings.

International Journal Of Molecular Epidemiology And Genetics

Truderung, Ole Ah OA; Sagi, Judit C JC; Semsei, Agnes F AF; Szalai, Csaba C

Publication Date: 2021

Variant appearance in text: CDK4: Arg24Cys

PubMed Link: 34853632

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The Challenging Melanoma Landscape: From Early Drug Discovery to Clinical Approval.

Cells

Matias, Mariana M; Pinho, Jacinta O JO; Penetra, Maria João MJ; Campos, Gonçalo G; Reis, Catarina Pinto CP; Gaspar, Maria Manuela MM

Publication Date: 2021-11-09

Variant appearance in text: CDK4: R24C

PubMed Link: 34831311

Variant Present in the following documents:

• Main text
• cells-10-03088.pdf

View BVdb publication page

---

Dental Pulp Stem Cells Derived From Adult Human Third Molar Tooth: A Brief Review.

Frontiers In Cell And Developmental Biology

Al Madhoun, Ashraf A; Sindhu, Sardar S; Haddad, Dania D; Atari, Maher M; Ahmad, Rasheed R; Al-Mulla, Fahd F

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 34712658

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas.

Iscience

Parekh, Udit U; McDonald, Daniella D; Dailamy, Amir A; Wu, Yan Y; Cordes, Thekla T; Zhang, Kun K; Tipps, Ann A; Metallo, Christian C; Mali, Prashant P

Publication Date: 2021-10-22

Variant appearance in text: CDK4: R24C

PubMed Link: 34646987

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

---

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

---

CDK4, CDK6/cyclin-D1 Complex Inhibition and Radiotherapy for Cancer Control: A Role for Autophagy.

International Journal Of Molecular Sciences

Nardone, Valerio V; Barbarino, Marcella M; Angrisani, Antonio A; Correale, Pierpaolo P; Pastina, Pierpaolo P; Cappabianca, Salvatore S; Reginelli, Alfonso A; Mutti, Luciano L; Miracco, Clelia C; Giannicola, Rocco R; Giordano, Antonio A; Pirtoli, Luigi L

Publication Date: 2021-08-04

Variant appearance in text: CDK4: R24C

PubMed Link: 34445095

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Familial Melanoma and Susceptibility Genes: A Review of the Most Common Clinical and Dermoscopic Phenotypic Aspect, Associated Malignancies and Practical Tips for Management.

Journal Of Clinical Medicine

Zocchi, Lamberto L; Lontano, Alberto A; Merli, Martina M; Dika, Emi E; Nagore, Eduardo E; Quaglino, Pietro P; Puig, Susana S; Ribero, Simone S

Publication Date: 2021-08-23

Variant appearance in text: CDK4: Arg24Cys

PubMed Link: 34442055

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy.

Cancers

Verdon, Daniel J DJ; Jenkins, Misty R MR

Publication Date: 2021-08-23

Variant appearance in text: CDK4: R24C

PubMed Link: 34439399

Variant Present in the following documents:

• Main text
• cancers-13-04245.pdf

View BVdb publication page

---

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy.

Cell Reports

Terranova, Christopher J CJ; Tang, Ming M; Maitituoheti, Mayinuer M; Raman, Ayush T AT; Ghosh, Archit K AK; Schulz, Jonathan J; Amin, Samir B SB; Orouji, Elias E; Tomczak, Katarzyna K; Sarkar, Sharmistha S; Oba, Junna J; Creasy, Caitlin C; Wu, Chang-Jiun CJ; Khan, Samia S; Lazcano, Rossana R; Wani, Khalida K; Singh, Anand A; Barrodia, Praveen P; Zhao, Dongyu D; Chen, Kaifu K; Haydu, Lauren E LE; Wang, Wei-Lien WL; Lazar, Alexander J AJ; Woodman, Scott E SE; Bernatchez, Chantale C; Rai, Kunal K

Publication Date: 2021-07-20

Variant appearance in text: CDK4: R24C

PubMed Link: 34289358

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Tumor rejection in Cblb -/- mice depends on IL-9 and Th9 cells.

Journal For Immunotherapy Of Cancer

Schanz, Oliver O; Cornez, Isabelle I; Yajnanarayana, Sowmya Parampalli SP; David, Friederike Sophie FS; Peer, Sebastian S; Gruber, Thomas T; Krawitz, Peter P; Brossart, Peter P; Heine, Annkristin A; Landsberg, Jenny J; Baier, Gottfried G; Wolf, Dominik D

Publication Date: 2021-07

Variant appearance in text: CDK4: R24C

PubMed Link: 34272310

Variant Present in the following documents:

• Main text
• jitc-2021-002889.pdf

View BVdb publication page

---

Tumor rejection in Cblb-/- mice depends on IL-9 and Th9 cells.

Journal For Immunotherapy Of Cancer

Schanz, Oliver O; Cornez, Isabelle I; Yajnanarayana, Sowmya Parampalli SP; David, Friederike Sophie FS; Peer, Sebastian S; Gruber, Thomas T; Krawitz, Peter P; Brossart, Peter P; Heine, Annkristin A; Landsberg, Jenny J; Baier, Gottfried G; Wolf, Dominik D

Publication Date: 2021-07

Variant appearance in text: CDK4: R24C

PubMed Link: 34272310

Variant Present in the following documents:

• Main text
• jitc-2021-002889.pdf

View BVdb publication page

---

Longitudinal Genomic Evolution of Conventional Papillary Thyroid Cancer With Brain Metastasis.

Frontiers In Oncology

Luo, Han H; Liao, Xue X; Qin, Yun Y; Hou, Qianqian Q; Xue, Zhinan Z; Liu, Yang Y; Shen, Feiyang F; Wang, Yuelan Y; Jiang, Yong Y; Song, Linlin L; Chen, Haining H; Zhang, Lingyun L; Wei, Tao T; Dai, Lunzhi L; Yang, Li L; Zhang, Wei W; Li, Zhihui Z; Xu, Heng H; Zhu, Jingqiang J; Shu, Yang Y

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 34249677

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations.

Plos One

Kerzeli, Iliana K IK; Lord, Martin M; Doroszko, Milena M; Elgendy, Ramy R; Chourlia, Aikaterini A; Stepanek, Ivan I; Larsson, Elinor E; van Hooren, Luuk L; Nelander, Sven S; Malmstrom, Per-Uno PU; Dragomir, Anca A; Segersten, Ulrika U; Mangsbo, Sara M SM

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 34232958

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Establishment of a Novel In Vitro Model of Endometriosis with Oncogenic KRAS and PIK3CA Mutations for Understanding the Underlying Biology and Molecular Pathogenesis.

Cancers

Hossain, Mohammad Mahmud MM; Nakayama, Kentaro K; Shanta, Kamrunnahar K; Razia, Sultana S; Ishikawa, Masako M; Ishibashi, Tomoka T; Yamashita, Hitomi H; Sato, Seiya S; Iida, Kouji K; Kanno, Kosuke K; Ishikawa, Noriyoshi N; Kiyono, Tohru T; Kyo, Satoru S

Publication Date: 2021-06-25

Variant appearance in text: CDK4: R24C

PubMed Link: 34202354

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Porcine pancreatic ductal epithelial cells transformed with KRASG12D and SV40T are tumorigenic.

Scientific Reports

Bailey, Katie L KL; Cartwright, Sara B SB; Patel, Neesha S NS; Remmers, Neeley N; Lazenby, Audrey J AJ; Hollingsworth, Michael A MA; Carlson, Mark A MA

Publication Date: 2021-06-28

Variant appearance in text: CDK4: R24C

PubMed Link: 34183736

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Cutaneous Melanoma Classification: The Importance of High-Throughput Genomic Technologies.

Frontiers In Oncology

Scatena, Cristian C; Murtas, Daniela D; Tomei, Sara S

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 34123788

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: CDK4: R24C

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 26

View BVdb publication page

---

CDK4/6 Inhibitors in Melanoma: A Comprehensive Review.

Cells

Garutti, Mattia M; Targato, Giada G; Buriolla, Silvia S; Palmero, Lorenza L; Minisini, Alessandro Marco AM; Puglisi, Fabio F

Publication Date: 2021-05-28

Variant appearance in text: CDK4: R24C

PubMed Link: 34071228

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Resistance to Targeted Therapy and RASSF1A Loss in Melanoma: What Are We Missing?

International Journal Of Molecular Sciences

McKenna, Stephanie S; García-Gutiérrez, Lucía L

Publication Date: 2021-05-12

Variant appearance in text: CDK4: R24C

PubMed Link: 34066022

Variant Present in the following documents:

• Main text
• ijms-22-05115.pdf

View BVdb publication page

---

The transcriptome of wild-type and immortalized corneal epithelial cells.

Scientific Data

Furuya, Kai K; Wu, Tao T; Orimoto, Ai A; Sugano, Eriko E; Tomita, Hiroshi H; Kiyono, Tohru T; Kurose, Takahiro T; Takai, Yoshihiro Y; Fukuda, Tomokazu T

Publication Date: 2021-05-07

Variant appearance in text: CDK4: R24C

PubMed Link: 33963195

Variant Present in the following documents:

• Main text

View BVdb publication page

---

3'UTR-CDKN2A and CDK4 Germline Variants Are Associated With Susceptibility to Cutaneous Melanoma.

In Vivo (Athens, Greece)

Tovar-Parra, David D; Gil-Quiñones, Sebastián Ramiro SR; Nova, John J; Gutiérrez-Castañeda, Luz D LD

Publication Date: 2021

Variant appearance in text: CDK4: R24C; rs11547328

PubMed Link: 33910831

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Cellular models of development of ovarian high-grade serous carcinoma: A review of cell of origin and mechanisms of carcinogenesis.

Cell Proliferation

Mei, Jie J; Tian, Huixiang H; Huang, Hsuan-Shun HS; Hsu, Che-Fang CF; Liou, Yuligh Y; Wu, Nayiyuan N; Zhang, Wei W; Chu, Tang-Yuan TY

Publication Date: 2021-05

Variant appearance in text: CDK4: R24C

PubMed Link: 33768671

Variant Present in the following documents:

• Main text
• CPR-54-e13029.pdf

View BVdb publication page

---

Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling.

Nature Communications

Yang, Chen C; Tian, Chengzhe C; Hoffman, Timothy E TE; Jacobsen, Nicole K NK; Spencer, Sabrina L SL

Publication Date: 2021-03-19

Variant appearance in text: CDK4: R24C

PubMed Link: 33741929

Variant Present in the following documents:

• 41467_2021_21549_MOESM1_ESM.pdf

View BVdb publication page

---

Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells.

Iscience

Fukuda, Tomokazu T; Furuya, Kai K; Takahashi, Kouhei K; Orimoto, Ai A; Sugano, Eriko E; Tomita, Hiroshi H; Kashiwagi, Sayo S; Kiyono, Tohru T; Ishii, Tsuyoshi T

Publication Date: 2021-01-22

Variant appearance in text: CDK4: R24C

PubMed Link: 33437932

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics

Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM

Publication Date: 2020-12

Variant appearance in text: CDK4: 70C>T; R24C

PubMed Link: 33230298

Variant Present in the following documents:

• NIHMS1637640-supplement-SuppData1.xlsx, sheet 1

View BVdb publication page

---

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.

Cell Reports

Maitituoheti, Mayinuer M; Keung, Emily Z EZ; Tang, Ming M; Yan, Liang L; Alam, Hunain H; Han, Guangchun G; Singh, Anand K AK; Raman, Ayush T AT; Terranova, Christopher C; Sarkar, Sharmistha S; Orouji, Elias E; Amin, Samir B SB; Sharma, Sneha S; Williams, Maura M; Samant, Neha S NS; Dhamdhere, Mayura M; Zheng, Norman N; Shah, Tara T; Shah, Amiksha A; Axelrad, Jacob B JB; Anvar, Nazanin E NE; Lin, Yu-Hsi YH; Jiang, Shan S; Chang, Edward Q EQ; Ingram, Davis R DR; Wang, Wei-Lien WL; Lazar, Alexander A; Lee, Min Gyu MG; Muller, Florian F; Wang, Linghua L; Ying, Haoqiang H; Rai, Kunal K

Publication Date: 2020-10-20

Variant appearance in text: CDK4: R24C

PubMed Link: 33086062

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients.

Scientific Reports

Aoude, Lauren G LG; Bonazzi, Vanessa F VF; Brosda, Sandra S; Patel, Kalpana K; Koufariotis, Lambros T LT; Oey, Harald H; Nones, Katia K; Wood, Scott S; Pearson, John V JV; Lonie, James M JM; Arneil, Melissa M; Atkinson, Victoria V; Smithers, B Mark BM; Waddell, Nicola N; Barbour, Andrew P AP

Publication Date: 2020-10-19

Variant appearance in text: CDK4: R24C

PubMed Link: 33077847

Variant Present in the following documents:

• Main text
• 41598_2020_74956_MOESM1_ESM.pdf
• 41598_2020_Article_74956.pdf

View BVdb publication page

---

Genetic Alterations in the INK4a/ARF Locus: Effects on Melanoma Development and Progression.

Biomolecules

Ming, Zizhen Z; Lim, Su Yin SY; Rizos, Helen H

Publication Date: 2020-10-15

Variant appearance in text: CDK4: Arg24Cys

PubMed Link: 33076392

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Immortalization of human hepatocytes from biliary atresia with CDK4R24C, cyclin D1, and TERT for cytochrome P450 induction testing.

Scientific Reports

Nishiwaki, Manami M; Toyoda, Masashi M; Oishi, Yoshie Y; Ishida, Seiichi S; Horiuchi, Shin-Ichiro SI; Makino-Itou, Hatsune H; Kimura, Tohru T; Ohno, Shin-Ichi SI; Ohkura, Takashi T; Enosawa, Shin S; Akutsu, Hidenori H; Nakazawa, Atsuko A; Kasahara, Mureo M; Kiyono, Tohru T; Umezawa, Akihiro A

Publication Date: 2020-10-15

Variant appearance in text: CDK4: R24C

PubMed Link: 33060611

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs11547328

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Humanized Rodent Models for Cancer Research.

Frontiers In Oncology

Tian, Huimin H; Lyu, Yanan Y; Yang, Yong-Guang YG; Hu, Zheng Z

Publication Date: 2020

Variant appearance in text: CDK4: R24C

PubMed Link: 33042811

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The multifaceted role of cell cycle regulators in the coordination of growth and metabolism.

The Febs Journal

Huber, Katharina K; Mestres-Arenas, Alberto A; Fajas, Lluis L; Leal-Esteban, Lucia C LC

Publication Date: 2021-06

Variant appearance in text: CDK4: R24C

PubMed Link: 33030287

Variant Present in the following documents:

• Main text

View BVdb publication page

---