Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.
British Journal Of Cancer
Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R
Publication Date: 2022-12-22
Variant appearance in text: TP53: 359A>G; Lys120Arg
Genomic Profiling of Bronchoalveolar Lavage Fluid in Lung Cancer.
Cancer Research
Nair, Viswam S VS; Hui, Angela Bik-Yu AB; Chabon, Jacob J JJ; Esfahani, Mohammad S MS; Stehr, Henning H; Nabet, Barzin Y BY; Zhou, Li L; Chaudhuri, Aadel A AA; Benson, Jalen J; Ayers, Kelsey K; Bedi, Harmeet H; Ramsey, Meghan M; Van Wert, Ryan R; Antic, Sanja S; Lui, Natalie N; Backhus, Leah L; Berry, Mark M; Sung, Arthur W AW; Massion, Pierre P PP; Shrager, Joseph B JB; Alizadeh, Ash A AA; Diehn, Maximilian M
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.
Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.
Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.
Npj Breast Cancer
Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S
Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.
Jto Clinical And Research Reports
Thompson, Jeffrey C JC; Aggarwal, Charu C; Wong, Janeline J; Nimgaonkar, Vivek V; Hwang, Wei-Ting WT; Andronov, Michelle M; Dibardino, David M DM; Hutchinson, Christoph T CT; Ma, Kevin C KC; Lanfranco, Anthony A; Moon, Edmund E; Haas, Andrew R AR; Singh, Aditi P AP; Ciunci, Christine A CA; Marmarelis, Melina M; D'Avella, Christopher C; Cohen, Justine V JV; Bauml, Joshua M JM; Cohen, Roger B RB; Langer, Corey J CJ; Vachani, Anil A; Carpenter, Erica L EL
Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.
Cell Reports
Zhang, Yiqun Y; Chen, Fengju F; Pleasance, Erin E; Williamson, Laura L; Grisdale, Cameron J CJ; Titmuss, Emma E; Laskin, Janessa J; Jones, Steven J M SJM; Cortes-Ciriano, Isidro I; Marra, Marco A MA; Creighton, Chad J CJ
Publication Date: 2021-11-16
Variant appearance in text: TP53: 359A>G; Lys120Arg
Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.
Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Molecular profiling of soft-tissue sarcomas with FoundationOne® Heme identifies potential targets for sarcoma therapy: a single-centre experience.
Therapeutic Advances In Medical Oncology
Scheipl, Susanne S; Brcic, Iva I; Moser, Tina T; Fischerauer, Stefan S; Riedl, Jakob J; Bergovec, Marko M; Smolle, Maria M; Posch, Florian F; Gerger, Armin A; Pichler, Martin M; Stoeger, Herbert H; Leithner, Andreas A; Heitzer, Ellen E; Liegl-Atzwanger, Bernadette B; Szkandera, Joanna J
Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.
Molecular Oncology
Marx, Christian C; Sonnemann, Jürgen J; Beyer, Mandy M; Maddocks, Oliver D K ODK; Lilla, Sergio S; Hauzenberger, Irene I; Piée-Staffa, Andrea A; Siniuk, Kanstantsin K; Nunna, Suneetha S; Marx-Blümel, Lisa L; Westermann, Martin M; Wagner, Tobias T; Meyer, Felix B FB; Thierbach, René R; Mullins, Christina S CS; Kdimati, Said S; Linnebacher, Michael M; Neri, Francesco F; Heinzel, Thorsten T; Wang, Zhao-Qi ZQ; Krämer, Oliver H OH
Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.
Molecular Oncology
Marx, Christian C; Sonnemann, Jürgen J; Beyer, Mandy M; Maddocks, Oliver D K ODK; Lilla, Sergio S; Hauzenberger, Irene I; Piée-Staffa, Andrea A; Siniuk, Kanstantsin K; Nunna, Suneetha S; Marx-Blümel, Lisa L; Westermann, Martin M; Wagner, Tobias T; Meyer, Felix B FB; Thierbach, René R; Mullins, Christina S CS; Kdimati, Said S; Linnebacher, Michael M; Neri, Francesco F; Heinzel, Thorsten T; Wang, Zhao-Qi ZQ; Krämer, Oliver H OH
Role of next generation sequencing-based liquid biopsy in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: impact of STK11, KRAS and TP53 mutations and co-mutations on outcome.
Translational Lung Cancer Research
Pavan, Alberto A; Bragadin, Andrea Boscolo AB; Calvetti, Lorenzo L; Ferro, Alessandra A; Zulato, Elisabetta E; Attili, Ilaria I; Nardo, Giorgia G; Dal Maso, Alessandro A; Frega, Stefano S; Menin, Andrea Giovanni AG; Fassan, Matteo M; Calabrese, Fiorella F; Pasello, Giulia G; Guarneri, Valentina V; Aprile, Giuseppe G; Conte, PierFranco P; Rosell, Rafael R; Indraccolo, Stefano S; Bonanno, Laura L
Suberoylanilide hydroxamic acid enhances the radiosensitivity of lung cancer cells through acetylated wild-type and mutant p53-dependent modulation of mitochondrial apoptosis.
Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates.
Nature Communications
Farkas, Marina M; Hashimoto, Hideharu H; Bi, Yingtao Y; Davuluri, Ramana V RV; Resnick-Silverman, Lois L; Manfredi, James J JJ; Debler, Erik W EW; McMahon, Steven B SB
Inferring the molecular and phenotypic impact of amino acid variants with MutPred2.
Nature Communications
Pejaver, Vikas V; Urresti, Jorge J; Lugo-Martinez, Jose J; Pagel, Kymberleigh A KA; Lin, Guan Ning GN; Nam, Hyun-Jun HJ; Mort, Matthew M; Cooper, David N DN; Sebat, Jonathan J; Iakoucheva, Lilia M LM; Mooney, Sean D SD; Radivojac, Predrag P
Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.
Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.
Blood
DiNardo, C D CD; Tiong, I S IS; Quaglieri, A A; MacRaild, S S; Loghavi, S S; Brown, F C FC; Thijssen, R R; Pomilio, G G; Ivey, A A; Salmon, J M JM; Glytsou, C C; Fleming, S A SA; Zhang, Q Q; Ma, H H; Patel, K P KP; Kornblau, S M SM; Xu, Z Z; Chua, C C CC; Chen, Xufeng X; Blombery, P P; Flensburg, C C; Cummings, N N; Aifantis, I I; Kantarjian, H H; Huang, D C S DCS; Roberts, A W AW; Majewski, I J IJ; Konopleva, M M; Wei, A H AH
Genomics of lethal prostate cancer at diagnosis and castration resistance.
The Journal Of Clinical Investigation
Mateo, Joaquin J; Seed, George G; Bertan, Claudia C; Rescigno, Pasquale P; Dolling, David D; Figueiredo, Ines I; Miranda, Susana S; Nava Rodrigues, Daniel D; Gurel, Bora B; Clarke, Matthew M; Atkin, Mark M; Chandler, Rob R; Messina, Carlo C; Sumanasuriya, Semini S; Bianchini, Diletta D; Barrero, Maialen M; Petermolo, Antonella A; Zafeiriou, Zafeiris Z; Fontes, Mariane M; Perez-Lopez, Raquel R; Tunariu, Nina N; Fulton, Ben B; Jones, Robert R; McGovern, Ursula U; Ralph, Christy C; Varughese, Mohini M; Parikh, Omi O; Jain, Suneil S; Elliott, Tony T; Sandhu, Shahneen S; Porta, Nuria N; Hall, Emma E; Yuan, Wei W; Carreira, Suzanne S; de Bono, Johann S JS
Clinical and genetic analysis of melanomas arising in acral sites.
European Journal Of Cancer (Oxford, England : 1990)
Zaremba, Anne A; Murali, Rajmohan R; Jansen, Philipp P; Möller, Inga I; Sucker, Antje A; Paschen, Annette A; Zimmer, Lisa L; Livingstone, Elisabeth E; Brinker, Titus J TJ; Hadaschik, Eva E; Franklin, Cindy C; Roesch, Alexander A; Ugurel, Selma S; Schadendorf, Dirk D; Griewank, Klaus G KG; Cosgarea, Ioana I