TP53 c.359A>G ;(p.K120R)

Variant ID: 17-7579328-T-C

NM_000546.5(TP53):c.359A>G;(p.K120R)

This variant was identified in 117 publications

View GRCh38 version.




Publications:


An Ethanol Extract of Coptidis rhizoma Induces Apoptotic Cell Death in Induced Pluripotent Stem Cells and Suppresses Teratoma Formation.

Nutrients
Kim, Aeyung A; Baek, Su-Jin SJ; Shin, Sarah S; Lee, Seo-Young SY; Chung, Sun-Ku SK
Publication Date: 2023-05-18

Variant appearance in text: p53: K120R
PubMed Link: 37242247
Variant Present in the following documents:
  • nutrients-15-02364.pdf
View BVdb publication page



GADD34 activates p53 and may have utility as a marker of atherosclerosis.

Frontiers In Medicine
Tomiyoshi, Go G; Nakamura, Rika R; Shinmen, Natsuko N; Yoshida, Yoichi Y; Mine, Seiichiro S; Machida, Toshio T; Iwase, Katsuro K; Iwadate, Yasuo Y; Hiwasa, Takaki T; Kuroda, Hideyuki H
Publication Date: 2023

Variant appearance in text: p53: K120R
PubMed Link: 37228401
Variant Present in the following documents:
  • fmed-10-1128921.pdf
View BVdb publication page



Editorial: Role of p53 in cell metabolism, ferroptosis, and stemness.

Frontiers In Genetics
Lu, Jordan J; Zhang, Yanchun Y; Yang, Jiaxing J; Cui, Shufang S; Zhang, Jing J; Liu, Yanqing Y
Publication Date: 2023

Variant appearance in text: p53: K120R
PubMed Link: 37124615
Variant Present in the following documents:
  • Main text
  • fgene-14-1198641.pdf
View BVdb publication page



Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.

British Journal Of Cancer
Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R
Publication Date: 2022-12-22

Variant appearance in text: TP53: 359A>G; Lys120Arg
PubMed Link: 36550207
Variant Present in the following documents:
  • 41416_2022_2102_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Hao, Suisui S; Tong, Jingshan J; Jha, Anupma A; Risnik, Denise D; Lizardo, Darleny D; Lu, Xinyan X; Goel, Ajay A; Opresko, Patricia L PL; Yu, Jian J; Zhang, Lin L
Publication Date: 2022-12-20

Variant appearance in text: p53: K120R
PubMed Link: 36508676
Variant Present in the following documents:
  • pnas.2211775119.sapp.pdf
  • pnas.202211775.pdf
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 2
View BVdb publication page



Erratum: Mutant p53K120R expression enables a partial capacity to modulate metabolism.

Frontiers In Genetics
,
Publication Date: 2022

Variant appearance in text: p53: K120R
PubMed Link: 36468028
Variant Present in the following documents:
  • fgene-13-1088645.pdf
View BVdb publication page



Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology
Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W
Publication Date: 2022

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 36238300
Variant Present in the following documents:
  • Table_1.xlsx, sheet 4
View BVdb publication page



Mutant p53K120R expression enables a partial capacity to modulate metabolism.

Frontiers In Genetics
Monti, Paola P; Ravera, Silvia S; Speciale, Andrea A; Velkova, Irena I; Foggetti, Giorgia G; Degan, Paolo P; Fronza, Gilberto G; Menichini, Paola P
Publication Date: 2022

Variant appearance in text: TP53: K120R
PubMed Link: 36226181
Variant Present in the following documents:
  • Main text
  • DataSheet1.pdf
  • fgene-13-974662.pdf
View BVdb publication page



EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine
Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W
Publication Date: 2022-09-19

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 36123678
Variant Present in the following documents:
  • 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: p53: 359A>G
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Case Report: Pulmonary sarcomatoid carcinoma complicating TP53 mutation treated successfully with Tislelizumab combined with Anlotinib-a case report.

Frontiers In Genetics
Li, Yu-Feng YF; Zhao, Xin-Fei XF; Tian, Yue Y; Xiao, Xin-Yao XY; Yan, Cai-Yun CY; Shen, Hua H
Publication Date: 2022

Variant appearance in text: p53: K120R
PubMed Link: 35938033
Variant Present in the following documents:
  • Main text
  • fgene-13-949989.pdf
View BVdb publication page



Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications
Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M
Publication Date: 2022-07-23

Variant appearance in text: TP53: K120R
PubMed Link: 35871175
Variant Present in the following documents:
  • 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Genomic Profiling of Bronchoalveolar Lavage Fluid in Lung Cancer.

Cancer Research
Nair, Viswam S VS; Hui, Angela Bik-Yu AB; Chabon, Jacob J JJ; Esfahani, Mohammad S MS; Stehr, Henning H; Nabet, Barzin Y BY; Zhou, Li L; Chaudhuri, Aadel A AA; Benson, Jalen J; Ayers, Kelsey K; Bedi, Harmeet H; Ramsey, Meghan M; Van Wert, Ryan R; Antic, Sanja S; Lui, Natalie N; Backhus, Leah L; Berry, Mark M; Sung, Arthur W AW; Massion, Pierre P PP; Shrager, Joseph B JB; Alizadeh, Ash A AA; Diehn, Maximilian M
Publication Date: 2022-08-16

Variant appearance in text: TP53: K120R
PubMed Link: 35748739
Variant Present in the following documents:
  • can-22-0554_supplementary_data_suppst1-st9.xlsx, sheet 5
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: TP53: K120R
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
View BVdb publication page



Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.

Npj Breast Cancer
Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S
Publication Date: 2022-05-10

Variant appearance in text: TP53: K120R
PubMed Link: 35538119
Variant Present in the following documents:
  • 41523_2022_426_MOESM1_ESM.pdf
View BVdb publication page



Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.

Jto Clinical And Research Reports
Thompson, Jeffrey C JC; Aggarwal, Charu C; Wong, Janeline J; Nimgaonkar, Vivek V; Hwang, Wei-Ting WT; Andronov, Michelle M; Dibardino, David M DM; Hutchinson, Christoph T CT; Ma, Kevin C KC; Lanfranco, Anthony A; Moon, Edmund E; Haas, Andrew R AR; Singh, Aditi P AP; Ciunci, Christine A CA; Marmarelis, Melina M; D'Avella, Christopher C; Cohen, Justine V JV; Bauml, Joshua M JM; Cohen, Roger B RB; Langer, Corey J CJ; Vachani, Anil A; Carpenter, Erica L EL
Publication Date: 2022-04

Variant appearance in text: TP53: K120R
PubMed Link: 35392653
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.

Cell Reports
Zhang, Yiqun Y; Chen, Fengju F; Pleasance, Erin E; Williamson, Laura L; Grisdale, Cameron J CJ; Titmuss, Emma E; Laskin, Janessa J; Jones, Steven J M SJM; Cortes-Ciriano, Isidro I; Marra, Marco A MA; Creighton, Chad J CJ
Publication Date: 2021-11-16

Variant appearance in text: TP53: 359A>G; Lys120Arg
PubMed Link: 34788622
Variant Present in the following documents:
  • NIHMS1757901-supplement-2.xlsx, sheet 3
View BVdb publication page



An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation.

Science Advances
Yang, Xin X; Wang, Xingwu X; Li, Zhiming Z; Duan, Shoufu S; Li, Huan H; Jin, Jian J; Zhang, Zhiguo Z; Gu, Wei W
Publication Date: 2021-10-29

Variant appearance in text: p53: K120R
PubMed Link: 34705508
Variant Present in the following documents:
  • Main text
  • sciadv.abi6684.pdf
  • sciadv.abi6684_sm.pdf
View BVdb publication page



Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways.

International Journal Of Molecular Sciences
Kim, Bu-Yeo BY; Lee, Seo-Young SY; Chung, Sun-Ku SK
Publication Date: 2021-10-06

Variant appearance in text: p53: K120R
PubMed Link: 34639134
Variant Present in the following documents:
  • ijms-22-10793.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: TP53: K120R
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer.

Npj Breast Cancer
Bortolini Silveira, Amanda A; Bidard, François-Clément FC; Tanguy, Marie-Laure ML; Girard, Elodie E; Trédan, Olivier O; Dubot, Coraline C; Jacot, William W; Goncalves, Anthony A; Debled, Marc M; Levy, Christelle C; Ferrero, Jean-Marc JM; Jouannaud, Christelle C; Rios, Maria M; Mouret-Reynier, Marie-Ange MA; Dalenc, Florence F; Hego, Caroline C; Rampanou, Aurore A; Albaud, Benoit B; Baulande, Sylvain S; Berger, Frédérique F; Lemonnier, Jérôme J; Renault, Shufang S; Desmoulins, Isabelle I; Proudhon, Charlotte C; Pierga, Jean-Yves JY
Publication Date: 2021-09-09

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 34504096
Variant Present in the following documents:
  • 41523_2021_319_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Molecular profiling of soft-tissue sarcomas with FoundationOne® Heme identifies potential targets for sarcoma therapy: a single-centre experience.

Therapeutic Advances In Medical Oncology
Scheipl, Susanne S; Brcic, Iva I; Moser, Tina T; Fischerauer, Stefan S; Riedl, Jakob J; Bergovec, Marko M; Smolle, Maria M; Posch, Florian F; Gerger, Armin A; Pichler, Martin M; Stoeger, Herbert H; Leithner, Andreas A; Heitzer, Ellen E; Liegl-Atzwanger, Bernadette B; Szkandera, Joanna J
Publication Date: 2021

Variant appearance in text: TP53: K120R
PubMed Link: 34367342
Variant Present in the following documents:
  • sj-xlsx-1-tam-10.1177_17588359211029125.xlsx, sheet 1
View BVdb publication page



Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.

Molecular Oncology
Marx, Christian C; Sonnemann, Jürgen J; Beyer, Mandy M; Maddocks, Oliver D K ODK; Lilla, Sergio S; Hauzenberger, Irene I; Piée-Staffa, Andrea A; Siniuk, Kanstantsin K; Nunna, Suneetha S; Marx-Blümel, Lisa L; Westermann, Martin M; Wagner, Tobias T; Meyer, Felix B FB; Thierbach, René R; Mullins, Christina S CS; Kdimati, Said S; Linnebacher, Michael M; Neri, Francesco F; Heinzel, Thorsten T; Wang, Zhao-Qi ZQ; Krämer, Oliver H OH
Publication Date: 2021-12

Variant appearance in text: p53: K120R
PubMed Link: 34258881
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.

Molecular Oncology
Marx, Christian C; Sonnemann, Jürgen J; Beyer, Mandy M; Maddocks, Oliver D K ODK; Lilla, Sergio S; Hauzenberger, Irene I; Piée-Staffa, Andrea A; Siniuk, Kanstantsin K; Nunna, Suneetha S; Marx-Blümel, Lisa L; Westermann, Martin M; Wagner, Tobias T; Meyer, Felix B FB; Thierbach, René R; Mullins, Christina S CS; Kdimati, Said S; Linnebacher, Michael M; Neri, Francesco F; Heinzel, Thorsten T; Wang, Zhao-Qi ZQ; Krämer, Oliver H OH
Publication Date: 2021-12

Variant appearance in text: p53: K120R
PubMed Link: 34258881
Variant Present in the following documents:
  • Main text
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10
View BVdb publication page



Map of ubiquitin-like post-translational modifications in chronic lymphocytic leukemia. Role of p53 lysine 120 NEDDylation.

Leukemia
Bravo-Navas, Sara S; Yáñez, Lucrecia L; Romón, Íñigo Í; Briz, Montserrat M; Domínguez-García, Juan José JJ; Pipaón, Carlos C
Publication Date: 2021-12

Variant appearance in text: p53: K120R
PubMed Link: 33966047
Variant Present in the following documents:
  • Main text
View BVdb publication page



The nucleolus functions as the compartment for histone H2B protein degradation.

Iscience
Liu, Yanping Y; Wang, Yufei Y; Yang, Lu L; Sun, Feng F; Li, Sheng S; Wang, Yequan Y; Zhang, Guo-An GA; Dong, Tingting T; Zhang, Lei-Lei LL; Duan, Wanglin W; Zhang, Xiaojun X; Cui, Wen W; Chen, Su S
Publication Date: 2021-04-23

Variant appearance in text: p53: K120R
PubMed Link: 33796843
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



An unexpected role for p53 in regulating cancer cell-intrinsic PD-1 by acetylation.

Science Advances
Cao, Zhijie Z; Kon, Ning N; Liu, Yajing Y; Xu, Wenbin W; Wen, Jia J; Yao, Han H; Zhang, Mi M; Wu, Zhen Z; Yan, Xiaojun X; Zhu, Wei-Guo WG; Gu, Wei W; Wang, Donglai D
Publication Date: 2021-03

Variant appearance in text: p53: K120R
PubMed Link: 33789902
Variant Present in the following documents:
  • Main text
View BVdb publication page



An unexpected role for p53 in regulating cancer cell-intrinsic PD-1 by acetylation.

Science Advances
Cao, Zhijie Z; Kon, Ning N; Liu, Yajing Y; Xu, Wenbin W; Wen, Jia J; Yao, Han H; Zhang, Mi M; Wu, Zhen Z; Yan, Xiaojun X; Zhu, Wei-Guo WG; Gu, Wei W; Wang, Donglai D
Publication Date: 2021-03

Variant appearance in text: p53: K120R
PubMed Link: 33789902
Variant Present in the following documents:
  • Main text
View BVdb publication page



Role of next generation sequencing-based liquid biopsy in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: impact of STK11, KRAS and TP53 mutations and co-mutations on outcome.

Translational Lung Cancer Research
Pavan, Alberto A; Bragadin, Andrea Boscolo AB; Calvetti, Lorenzo L; Ferro, Alessandra A; Zulato, Elisabetta E; Attili, Ilaria I; Nardo, Giorgia G; Dal Maso, Alessandro A; Frega, Stefano S; Menin, Andrea Giovanni AG; Fassan, Matteo M; Calabrese, Fiorella F; Pasello, Giulia G; Guarneri, Valentina V; Aprile, Giuseppe G; Conte, PierFranco P; Rosell, Rafael R; Indraccolo, Stefano S; Bonanno, Laura L
Publication Date: 2021-01

Variant appearance in text: TP53: K120R
PubMed Link: 33569305
Variant Present in the following documents:
  • tlcr-10-01-202-supplementary.pdf
View BVdb publication page



Suberoylanilide hydroxamic acid enhances the radiosensitivity of lung cancer cells through acetylated wild-type and mutant p53-dependent modulation of mitochondrial apoptosis.

The Journal Of International Medical Research
Wu, Kan K; Chen, Xueqin X; Chen, Xufeng X; Zhang, Shirong S; Xu, Yasi Y; Xia, Bing B; Ma, Shenglin S
Publication Date: 2021-02

Variant appearance in text: p53: K120R
PubMed Link: 33557658
Variant Present in the following documents:
  • Main text
  • 10.1177_0300060520981545.pdf
View BVdb publication page



Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates.

Nature Communications
Farkas, Marina M; Hashimoto, Hideharu H; Bi, Yingtao Y; Davuluri, Ramana V RV; Resnick-Silverman, Lois L; Manfredi, James J JJ; Debler, Erik W EW; McMahon, Steven B SB
Publication Date: 2021-01-20

Variant appearance in text: p53: K120R
PubMed Link: 33473123
Variant Present in the following documents:
  • Main text
  • 41467_2020_Article_20783.pdf
  • 41467_2020_20783_MOESM1_ESM.pdf
View BVdb publication page



mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression.

Genes & Development
Kon, Ning N; Ou, Yang Y; Wang, Shang-Jui SJ; Li, Huan H; Rustgi, Anil K AK; Gu, Wei W
Publication Date: 2021-01-01

Variant appearance in text: p53: K120R
PubMed Link: 33303641
Variant Present in the following documents:
  • Main text
  • 59.pdf
View BVdb publication page



Inferring the molecular and phenotypic impact of amino acid variants with MutPred2.

Nature Communications
Pejaver, Vikas V; Urresti, Jorge J; Lugo-Martinez, Jose J; Pagel, Kymberleigh A KA; Lin, Guan Ning GN; Nam, Hyun-Jun HJ; Mort, Matthew M; Cooper, David N DN; Sebat, Jonathan J; Iakoucheva, Lilia M LM; Mooney, Sean D SD; Radivojac, Predrag P
Publication Date: 2020-11-20

Variant appearance in text: p53: K120R
PubMed Link: 33219223
Variant Present in the following documents:
  • 41467_2020_Article_19669.pdf
View BVdb publication page



USP7 negatively controls global DNA methylation by attenuating ubiquitinated histone-dependent DNMT1 recruitment.

Cell Discovery
Li, Jialun J; Wang, Ruiping R; Jin, Jianyu J; Han, Mengmeng M; Chen, Zhaosu Z; Gao, Yingying Y; Hu, Xueli X; Zhu, Haijun H; Gao, Huifang H; Lu, Kongbin K; Shao, Yanjiao Y; Lyu, Cong C; Lai, Weiyi W; Li, Pishun P; Hu, Guang G; Li, Jiwen J; Li, Dali D; Wang, Hailin H; Wu, Qihan Q; Wong, Jiemin J
Publication Date: 2020

Variant appearance in text: p53: K120R
PubMed Link: 32884836
Variant Present in the following documents:
  • Main text
  • 41421_2020_Article_188.pdf
View BVdb publication page



TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection.

Ebiomedicine
Klinakis, Apostolos A; Rampias, Theodoros T
Publication Date: 2020-08

Variant appearance in text: TP53: K120R
PubMed Link: 32739866
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Regulating tumor suppressor genes: post-translational modifications.

Signal Transduction And Targeted Therapy
Chen, Ling L; Liu, Shuang S; Tao, Yongguang Y
Publication Date: 2020-06-10

Variant appearance in text: p53: K120R
PubMed Link: 32532965
Variant Present in the following documents:
  • Main text
  • 41392_2020_Article_196.pdf
View BVdb publication page



Elimination of Teratogenic Human Induced Pluripotent Stem Cells by Bee Venom via Calcium-Calpain Pathway.

International Journal Of Molecular Sciences
Kim, Aeyung A; Lee, Seo-Young SY; Kim, Bu-Yeo BY; Chung, Sun-Ku SK
Publication Date: 2020-05-05

Variant appearance in text: p53: K120R
PubMed Link: 32380745
Variant Present in the following documents:
  • ijms-21-03265.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: TP53: K120R
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.

Blood
DiNardo, C D CD; Tiong, I S IS; Quaglieri, A A; MacRaild, S S; Loghavi, S S; Brown, F C FC; Thijssen, R R; Pomilio, G G; Ivey, A A; Salmon, J M JM; Glytsou, C C; Fleming, S A SA; Zhang, Q Q; Ma, H H; Patel, K P KP; Kornblau, S M SM; Xu, Z Z; Chua, C C CC; Chen, Xufeng X; Blombery, P P; Flensburg, C C; Cummings, N N; Aifantis, I I; Kantarjian, H H; Huang, D C S DCS; Roberts, A W AW; Majewski, I J IJ; Konopleva, M M; Wei, A H AH
Publication Date: 2020-03-12

Variant appearance in text: TP53: K120R
PubMed Link: 31932844
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Genomics of lethal prostate cancer at diagnosis and castration resistance.

The Journal Of Clinical Investigation
Mateo, Joaquin J; Seed, George G; Bertan, Claudia C; Rescigno, Pasquale P; Dolling, David D; Figueiredo, Ines I; Miranda, Susana S; Nava Rodrigues, Daniel D; Gurel, Bora B; Clarke, Matthew M; Atkin, Mark M; Chandler, Rob R; Messina, Carlo C; Sumanasuriya, Semini S; Bianchini, Diletta D; Barrero, Maialen M; Petermolo, Antonella A; Zafeiriou, Zafeiris Z; Fontes, Mariane M; Perez-Lopez, Raquel R; Tunariu, Nina N; Fulton, Ben B; Jones, Robert R; McGovern, Ursula U; Ralph, Christy C; Varughese, Mohini M; Parikh, Omi O; Jain, Suneil S; Elliott, Tony T; Sandhu, Shahneen S; Porta, Nuria N; Hall, Emma E; Yuan, Wei W; Carreira, Suzanne S; de Bono, Johann S JS
Publication Date: 2020-04-01

Variant appearance in text: TP53: 359A>G; K120R
PubMed Link: 31874108
Variant Present in the following documents:
  • jci-130-132031-s100.xlsx, sheet 1
  • jci-130-132031-s102.xlsx, sheet 1
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Stepwise multipolyubiquitination of p53 by the E6AP-E6 ubiquitin ligase complex.

The Journal Of Biological Chemistry
Masuda, Yuji Y; Saeki, Yasushi Y; Arai, Naoko N; Kawai, Hidehiko H; Kukimoto, Iwao I; Tanaka, Keiji K; Masutani, Chikahide C
Publication Date: 2019-10-11

Variant appearance in text: p53: K120R
PubMed Link: 31492752
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KAT5 Negatively regulates the proliferation of prostate cancer LNCaP cells via the caspase 3-dependent apoptosis pathway.

Animal Cells And Systems
Kim, Chul-Hong CH; Lee, Dong Ho DH
Publication Date: 2019

Variant appearance in text: p53: K120R
PubMed Link: 31489246
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  • Main text
  • TACS_23_1644372.pdf
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Clinical and genetic analysis of melanomas arising in acral sites.

European Journal Of Cancer (Oxford, England : 1990)
Zaremba, Anne A; Murali, Rajmohan R; Jansen, Philipp P; Möller, Inga I; Sucker, Antje A; Paschen, Annette A; Zimmer, Lisa L; Livingstone, Elisabeth E; Brinker, Titus J TJ; Hadaschik, Eva E; Franklin, Cindy C; Roesch, Alexander A; Ugurel, Selma S; Schadendorf, Dirk D; Griewank, Klaus G KG; Cosgarea, Ioana I
Publication Date: 2019-09

Variant appearance in text: TP53: K120R
PubMed Link: 31419753
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Abrogation of FBW7α-dependent p53 degradation enhances p53's function as a tumor suppressor.

The Journal Of Biological Chemistry
Tripathi, Vivek V; Kaur, Ekjot E; Kharat, Suhas Sampat SS; Hussain, Mansoor M; Damodaran, Arun Prasath AP; Kulshrestha, Swati S; Sengupta, Sagar S
Publication Date: 2019-09-06

Variant appearance in text: p53: K120R
PubMed Link: 31346036
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p53 modifications: exquisite decorations of the powerful guardian.

Journal Of Molecular Cell Biology
Liu, Yanqing Y; Tavana, Omid O; Gu, Wei W
Publication Date: 2019-07-19

Variant appearance in text: p53: K120R
PubMed Link: 31282934
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Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53.

Embo Reports
Wang, Yufei Y; Yang, Lu L; Zhang, Xiaojun X; Cui, Wen W; Liu, Yanping Y; Sun, Qin-Ru QR; He, Qing Q; Zhao, Shiyan S; Zhang, Guo-An GA; Wang, Yequan Y; Chen, Su S
Publication Date: 2019-07

Variant appearance in text: p53: K120R
PubMed Link: 31267712
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The RNF20/40 complex regulates p53-dependent gene transcription and mRNA splicing.

Journal Of Molecular Cell Biology
Wu, Chen C; Cui, Yaqi Y; Liu, Xiuhua X; Zhang, Feng F; Lu, Lin-Yu LY; Yu, Xiaochun X
Publication Date: 2020-02-20

Variant appearance in text: p53: K120R
PubMed Link: 31152661
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Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks.

Cell Cycle (Georgetown, Tex.)
Catizone, Allison N AN; Good, Charly Ryan CR; Alexander, Katherine A KA; Berger, Shelley L SL; Sammons, Morgan A MA
Publication Date: 2019-04

Variant appearance in text: p53: K120R
PubMed Link: 30966857
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  • kccy-18-08-1593643.pdf
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The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B.

Hepatology (Baltimore, Md.)
Ren, Laifeng L; Zeng, Ming M; Tang, Zizhi Z; Li, Mingyuan M; Wang, Xiaojun X; Xu, Yang Y; Weng, Yuding Y; Wang, Xiaobo X; Wang, Huan H; Guo, Liandi L; Zuo, Bing B; Wang, Xin X; Wang, Si S; Lou, Jiangyan J; Tang, Yaxiong Y; Mu, Dezhi D; Zheng, Ning N; Wu, Xianhui X; Han, Junhong J; Carr, Antony M AM; Jeggo, Penelope P; Liu, Cong C
Publication Date: 2019-06

Variant appearance in text: p53: K120R
PubMed Link: 30791110
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Dual Targeting of EGFR and IGF1R in the TNFAIP8 Knockdown Non-Small Cell Lung Cancer Cells.

Molecular Cancer Research : Mcr
Day, Timothy F TF; Kallakury, Bhaskar V S BVS; Ross, Jeffrey S JS; Voronel, Olga O; Vaidya, Shantashri S; Sheehan, Christine E CE; Kasid, Usha N UN
Publication Date: 2019-05

Variant appearance in text: p53: K120R
PubMed Link: 30647104
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