Publications:

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: ALK: 3700G>A; A1234T

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ALK: A1234T

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Mutational Profile and Clonal Evolution of Relapsed/Refractory Diffuse Large B-Cell Lymphoma.

Frontiers In Oncology

Lee, Boram B; Lee, Hyunwoo H; Cho, Junhun J; Yoon, Sang Eun SE; Kim, Seok Jin SJ; Park, Woong-Yang WY; Kim, Won Seog WS; Ko, Young Hyeh YH

Publication Date: 2021

Variant appearance in text: ALK: A1234T

PubMed Link: 33777778

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 1

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: ALK: 3700G>A

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM9_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ALK: A1234T

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Structure and energy based quantitative missense variant effect analysis provides insights into drug resistance mechanisms of anaplastic lymphoma kinase mutations.

Scientific Reports

Li, Jianzong J; Huang, Yue Y; Wu, Miaomiao M; Wu, Chuanfang C; Li, Xin X; Bao, Jinku J

Publication Date: 2018-07-13

Variant appearance in text: ALK: A1234T

PubMed Link: 30006516

Variant Present in the following documents:

• 41598_2018_28752_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Tumor Resistance against ALK Targeted Therapy-Where It Comes From and Where It Goes.

Cancers

Sharma, Geeta Geeta GG; Mota, Ines I; Mologni, Luca L; Patrucco, Enrico E; Gambacorti-Passerini, Carlo C; Chiarle, Roberto R

Publication Date: 2018-02-28

Variant appearance in text: ALK: A1234T

PubMed Link: 29495603

Variant Present in the following documents:

• Main text
• cancers-10-00062.pdf

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The role of anaplastic lymphoma kinase in pediatric cancers.

Cancer Science

Takita, Junko J

Publication Date: 2017-10

Variant appearance in text: ALK: A1234T

PubMed Link: 28756644

Variant Present in the following documents:

• Main text
• CAS-108-1913.pdf

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ALK: a tyrosine kinase target for cancer therapy.

Cold Spring Harbor Molecular Case Studies

Holla, Vijaykumar R VR; Elamin, Yasir Y YY; Bailey, Ann Marie AM; Johnson, Amber M AM; Litzenburger, Beate C BC; Khotskaya, Yekaterina B YB; Sanchez, Nora S NS; Zeng, Jia J; Shufean, Md Abu MA; Shaw, Kenna R KR; Mendelsohn, John J; Mills, Gordon B GB; Meric-Bernstam, Funda F; Simon, George R GR

Publication Date: 2017-01

Variant appearance in text: ALK: A1234T

PubMed Link: 28050598

Variant Present in the following documents:

• Main text
• HollaMCS001115.pdf

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: ALK: A1234T

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s4.xls, sheet 1

View BVdb publication page

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Anaplastic lymphoma kinase: Role in cancer and therapy perspective.

Cancer Biology & Therapy

Zhao, Zhihong Z; Verma, Vivek V; Zhang, Mutian M

Publication Date: 2015

Variant appearance in text: ALK: A1234T

PubMed Link: 26529396

Variant Present in the following documents:

• Main text

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: ALK: A1234T

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 3

View BVdb publication page

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Integrating in silico prediction methods, molecular docking, and molecular dynamics simulation to predict the impact of ALK missense mutations in structural perspective.

Biomed Research International

Doss, C George Priya CG; Chakraborty, Chiranjib C; Chen, Luonan L; Zhu, Hailong H

Publication Date: 2014

Variant appearance in text: ALK: A1234T

PubMed Link: 25054154

Variant Present in the following documents:

View BVdb publication page

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Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma.

Disease Models & Mechanisms

Chand, Damini D; Yamazaki, Yasuo Y; Ruuth, Kristina K; Schönherr, Christina C; Martinsson, Tommy T; Kogner, Per P; Attiyeh, Edward F EF; Maris, John J; Morozova, Olena O; Marra, Marco A MA; Ohira, Miki M; Nakagawara, Akira A; Sandström, Per-Erik PE; Palmer, Ruth H RH; Hallberg, Bengt B

Publication Date: 2013-03

Variant appearance in text: ALK: A1234T

PubMed Link: 23104988

Variant Present in the following documents:

• Main text

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Emerging importance of ALK in neuroblastoma.

Seminars In Cancer Biology

Azarova, Anna M AM; Gautam, Gargi G; George, Rani E RE

Publication Date: 2011-10

Variant appearance in text: ALK: A1234T

PubMed Link: 21945349

Variant Present in the following documents:

• Main text

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: ALK: A1234T

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

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Anaplastic lymphoma kinase: signalling in development and disease.

The Biochemical Journal

Palmer, Ruth H RH; Vernersson, Emma E; Grabbe, Caroline C; Hallberg, Bengt B

Publication Date: 2009-05-27

Variant appearance in text: ALK: A1234T

PubMed Link: 19459784

Variant Present in the following documents:

• Main text

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Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy.

Expert Review Of Anticancer Therapy

Webb, Thomas R TR; Slavish, Jake J; George, Rani E RE; Look, A Thomas AT; Xue, Liquan L; Jiang, Qin Q; Cui, Xiaoli X; Rentrop, Walter B WB; Morris, Stephan W SW

Publication Date: 2009-03

Variant appearance in text: ALK: A1234T

PubMed Link: 19275511

Variant Present in the following documents:

• Main text

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Activating mutations in ALK provide a therapeutic target in neuroblastoma.

Nature

George, Rani E RE; Sanda, Takaomi T; Hanna, Megan M; Fröhling, Stefan S; Luther, William W; Zhang, Jianming J; Ahn, Yebin Y; Zhou, Wenjun W; London, Wendy B WB; McGrady, Patrick P; Xue, Liquan L; Zozulya, Sergey S; Gregor, Vlad E VE; Webb, Thomas R TR; Gray, Nathanael S NS; Gilliland, D Gary DG; Diller, Lisa L; Greulich, Heidi H; Morris, Stephan W SW; Meyerson, Matthew M; Look, A Thomas AT

Publication Date: 2008-10-16

Variant appearance in text: ALK: A1234T

PubMed Link: 18923525

Variant Present in the following documents:

• Main text
• NIHMS68190-supplement-1.pdf
• nihms68190.pdf

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