Publications:

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Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer.

Nature Communications

Zhao, Shen S; Zhuang, Wu W; Han, Baohui B; Song, Zhengbo Z; Guo, Wei W; Luo, Feng F; Wu, Lin L; Hu, Yi Y; Wang, Huijuan H; Dong, Xiaorong X; Jiang, Da D; Wang, Mingxia M; Miao, Liyun L; Wang, Qian Q; Zhang, Junping J; Fu, Zhenming Z; Huang, Yihua Y; Xu, Chunwei C; Hu, Longyu L; Li, Lei L; Hu, Rong R; Yang, Yang Y; Li, Mengke M; Yang, Xiugao X; Zhang, Li L; Huang, Yan Y; Fang, Wenfeng W

Publication Date: 2023-06-12

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 37308490

Variant Present in the following documents:

• 41467_2023_39139_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

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EGFR p.V774M/p.L833V compound mutations in lung adenocarcinoma responded well to almonertinib: a case report.

Frontiers In Oncology

Pan, Hai H; Zhang, Linlin L; Meng, Fanlu F; Guan, Shasha S; Zhong, Diansheng D

Publication Date: 2023

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 37251951

Variant Present in the following documents:

• Main text
• fonc-13-1159308.pdf

View BVdb publication page

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: L833V

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

View BVdb publication page

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Uncommon EGFR-Mutant NSCLC-One Drug Does Not Fit All.

Jto Clinical And Research Reports

Wang, Yang Y; Arulananda, Surein S

Publication Date: 2023-04

Variant appearance in text: EGFR: L833V

PubMed Link: 36994309

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Overcoming CEP85L-ROS1, MKRN1-BRAF and MET amplification as rare, acquired resistance mutations to Osimertinib.

Frontiers In Oncology

Kian, Waleed W; Krayim, Bilal B; Alsana, Hadel H; Giles, Betsy B; Purim, Ofer O; Alguayn, Wafeek W; Alguayn, Farouq F; Peled, Nir N; Roisman, Laila C LC

Publication Date: 2023

Variant appearance in text: EGFR: L833V

PubMed Link: 36923435

Variant Present in the following documents:

• Main text
• fonc-13-1124949.pdf

View BVdb publication page

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Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study.

Jto Clinical And Research Reports

Ji, Jingran J; Aredo, Jacqueline V JV; Piper-Vallillo, Andrew A; Huppert, Laura L; Rotow, Julia K JK; Husain, Hatim H; Stewart, Susan S; Cobb, Rosemary R; Wakelee, Heather A HA; Blakely, Collin M CM; Wong, Melisa L ML; Gubens, Matthew A MA; Madani, Mohammad H MH; Digumarthy, Subba R SR; McCoach, Caroline C; Piotrowska, Zofia Z; Neal, Joel W JW; Riess, Jonathan W JW

Publication Date: 2023-03

Variant appearance in text: EGFR: L833V

PubMed Link: 36879929

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology

Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N

Publication Date: 2023-02-20

Variant appearance in text: EGFR: L833V

PubMed Link: 36808143

Variant Present in the following documents:

• 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs397517126

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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A L833V/H835L EGFR variant lung adenocarcinoma with skin metastasis: A case report and literature review.

Heliyon

Yang, Xian X; Yao, Yang Y; Zhu, Qing Q

Publication Date: 2022-12

Variant appearance in text: EGFR: L833V

PubMed Link: 36531621

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology

Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S

Publication Date: 2022

Variant appearance in text: EGFR: L833V

PubMed Link: 36425553

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: L833V

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Multiple mutations in the EGFR gene in lung cancer: a systematic review.

Translational Lung Cancer Research

Castañeda-González, Juan Pablo JP; Chaves, Juan José JJ; Parra-Medina, Rafael R

Publication Date: 2022-10

Variant appearance in text: EGFR: L833V

PubMed Link: 36386461

Variant Present in the following documents:

• Main text
• tlcr-11-10-2148.pdf

View BVdb publication page

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Concurrent TP53 mutations predict a poor prognosis of EGFR-mutant NSCLCs treated with TKIs: An updated systematic review and meta-analysis.

Oncology Letters

Lan, Bo B; Zhao, Na N; Du, Kang K; Leng, Baolang B

Publication Date: 2022-11

Variant appearance in text: EGFR: L833V

PubMed Link: 36238360

Variant Present in the following documents:

• ol-24-05-13504.pdf

View BVdb publication page

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Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology

Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W

Publication Date: 2022

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 36238300

Variant Present in the following documents:

• Table_1.xlsx, sheet 4

View BVdb publication page

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EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine

Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W

Publication Date: 2022-09-19

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 36123678

Variant Present in the following documents:

• 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Insensitivity to T790M mutation? A pooled analysis of outcomes following osimertinib for the treatment of NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Pharmacology

Hu, Shanliang S; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Wang, Zhen Z; Dong, Wei W

Publication Date: 2022

Variant appearance in text: EGFR: L833V

PubMed Link: 36091840

Variant Present in the following documents:

• Main text
• fphar-13-986962.pdf

View BVdb publication page

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Prognostic value of baseline genetic features and newly identified TP53 mutations in advanced breast cancer.

Molecular Oncology

Zhang, Lanxin L; Sun, Siwen S; Zhao, Xiaotian X; Liu, Jingwen J; Xu, Yang Y; Xu, Lingzhi L; Song, Chen C; Li, Na N; Yu, Jing J; Zhao, Shanshan S; Yu, Peiyao P; Fang, Fengqi F; Xie, Jiping J; Ji, Xuening X; Yu, Ruoying R; Ou, Qiuxiang Q; Zhao, Zuowei Z; Li, Man M

Publication Date: 2022-10

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 35971249

Variant Present in the following documents:

• MOL2-16-3689-s005.xlsx, sheet 1

View BVdb publication page

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T790M mutation positive squamous cell carcinoma transformation from EGFR-mutated lung adenocarcinoma after low dose erlotinib: A case report and literature review.

Medicine

Kusaba, Yusaku Y; Takeda, Yuichiro Y; Abe, Sakurako S; Tsukada, Akinari A; Naka, Go G

Publication Date: 2022-08-12

Variant appearance in text: EGFR: L833V

PubMed Link: 35960133

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2497T>G; L833V; rs397517126

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Osimertinib in non-small cell lung cancer with uncommon EGFR-mutations: a post-hoc subgroup analysis with pooled data from two phase II clinical trials.

Translational Lung Cancer Research

Eide, Inger Johanne Zwicky IJZ; Stensgaard, Simone S; Helland, Åslaug Å; Ekman, Simon S; Mellemgaard, Anders A; Hansen, Karin Holmskov KH; Cicenas, Saulius S; Koivunen, Jussi J; Grønberg, Bjørn Henning BH; Sørensen, Boe Sandahl BS; Brustugun, Odd Terje OT

Publication Date: 2022-06

Variant appearance in text: EGFR: L833V

PubMed Link: 35832438

Variant Present in the following documents:

• Main text
• tlcr-11-06-953.pdf

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Genomic profiling reveals non-small cell lung cancer with common mutations of EGFR exon 20 and exon 21: a case report.

Translational Cancer Research

Bi, Xiaojun X; Song, Pengyu P; Wang, Chengye C; Zhang, Xuefei X; Liu, Changhong C

Publication Date: 2022-05

Variant appearance in text: EGFR: L833V

PubMed Link: 35706785

Variant Present in the following documents:

• Main text
• tcr-11-05-1423.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: L833V

PubMed Link: 35606799

Variant Present in the following documents:

• Main text
• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1
• 41021_2022_Article_248.pdf

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: L833V

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG).

The Oncologist

Popat, Sanjay S; Hsia, Te-Chun TC; Hung, Jen-Yu JY; Jung, Hyun Ae HA; Shih, Jin-Yuan JY; Park, Cheol Kyu CK; Lee, Seung Hyeun SH; Okamoto, Tatsuro T; Ahn, Hee Kyung HK; Lee, Yong Chul YC; Sato, Yuki Y; Lee, Sung Sook SS; Mascaux, Celine C; Daoud, Hasan H; Märten, Angela A; Miura, Satoru S

Publication Date: 2022-04-05

Variant appearance in text: EGFR: L833V

PubMed Link: 35274704

Variant Present in the following documents:

• oyac022.pdf

View BVdb publication page

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The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology

Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q

Publication Date: 2021

Variant appearance in text: EGFR: L833V

PubMed Link: 35273907

Variant Present in the following documents:

• Table_8.xlsx, sheet 1

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: EGFR: Leu833Val

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology

Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X

Publication Date: 2021

Variant appearance in text: EGFR: L833V; rs397517126

PubMed Link: 35186718

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports

Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C

Publication Date: 2022-02-09

Variant appearance in text: EGFR: L833V

PubMed Link: 35140316

Variant Present in the following documents:

• 41598_2022_6239_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports

Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C

Publication Date: 2022-02-09

Variant appearance in text: EGFR: L833V

PubMed Link: 35140316

Variant Present in the following documents:

• 41598_2022_6239_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS platform.

Translational Cancer Research

Mayo de Las Casas, Clara C; Garzón-Ibañez, Mónica M; Jordana-Ariza, Núria N; Viteri-Ramírez, Santiago S; Moya-Horno, Irene I; Karachaliou, Niki N; Yeste, Zaira Z; Campos, Raquel R; Villatoro, Sergi S; Balada-Bel, Ariadna A; García-Peláez, Beatriz B; Reguart, Noemí N; Teixidó, Cristina C; Jantús, Eloisa E; Calabuig, Silvia S; Aguado, Cristina C; Giménez-Capitán, Ana A; Román-Lladó, Ruth R; Pérez-Rosado, Ana A; Catalán, Maria José MJ; Bertrán-Alamillo, Jordi J; García-Román, Silvia S; Rodriguez, Sonia S; Alonso, Lidia L; Aldeguer, Erika E; Martínez-Bueno, Alejandro A; González-Cao, Maria M; Aguilar Hernandez, Andrés A; Garcia-Mosquera, Juan J; de Los Llanos Gil, Maria M; Fernandez, Manuel M; Rosell, Rafael R; Molina-Vila, Miguel Ángel MÁ

Publication Date: 2019-01

Variant appearance in text: EGFR: L833V

PubMed Link: 35117060

Variant Present in the following documents:

• Main text
• tcr-08-S1-S3.pdf

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Investigation of EGFR mutations in non-small cell lung cancer usually undetectable by PCR methods.

Molecular And Clinical Oncology

Matsubara, Taisuke T; Nakajima, Eiji E; Namikawa, Haruka H; Ono, Shotaro S; Takada, Ikki I; Ohira, Tatsuo T; Morishita, Yukio Y; Miyazaki, Teruo T; Furukawa, Kinya K; Ikeda, Norihiko N

Publication Date: 2022-01

Variant appearance in text: EGFR: L833V

PubMed Link: 34881035

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Frontiers In Oncology

Lin, Xinqing X; Peng, Muyun M; Chen, Quanfang Q; Yuan, Mingming M; Chen, Rongrong R; Deng, Haiyi H; Deng, Jiaxi J; Liu, Ouqi O; Weng, Yuqing Y; Chen, Mingjiu M; Zhou, Chengzhi C

Publication Date: 2021

Variant appearance in text: EGFR: L833V

PubMed Link: 34869019

Variant Present in the following documents:

• Main text
• fonc-11-774156.pdf

View BVdb publication page

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The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Lee, Jessica K JK; Hazar-Rethinam, Mehlika M; Decker, Brennan B; Gjoerup, Ole O; Madison, Russell W RW; Lieber, Daniel S DS; Chung, Jon H JH; Schrock, Alexa B AB; Creeden, James J; Venstrom, Jeffrey J; Alexander, Brian B; Oxnard, Geoffrey R GR

Publication Date: 2022-02-15

Variant appearance in text: EGFR: L833V

PubMed Link: 34753780

Variant Present in the following documents:

• Main text
• 728.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: L833V

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Leu833Val

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Leu833Val

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: L833V

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

View BVdb publication page

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: L833V

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

View BVdb publication page

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Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature

Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV

Publication Date: 2021-09

Variant appearance in text: EGFR: 2497T>G; L833V

PubMed Link: 34526717

Variant Present in the following documents:

• 41586_2021_3898_MOESM1_ESM.pdf
• 41586_2021_Article_3898.pdf

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The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.

Esmo Open

Kirchner, M M; Kluck, K K; Brandt, R R; Volckmar, A-L AL; Penzel, R R; Kazdal, D D; Endris, V V; Neumann, O O; Seker-Cin, H H; Goldschmid, H H; Glade, J J; Allgäuer, M M; Kriegsmann, M M; Winter, H H; Muley, T T; Perner, S S; Frost, N N; Reck, M M; Fröhling, S S; Schirmacher, P P; Thomas, M M; Budczies, J J; Christopoulos, P P; Stenzinger, A A

Publication Date: 2021-10

Variant appearance in text: EGFR: Leu833Val

PubMed Link: 34487971

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

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A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers

Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC

Publication Date: 2021-07-20

Variant appearance in text: EGFR: L833V

PubMed Link: 34298851

Variant Present in the following documents:

• Main text
• cancers-13-03641.pdf

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Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Pathology Oncology Research : Por

Mao, Linlin L; Zhao, Weiwei W; Li, Xiaoxia X; Zhang, Shangfei S; Zhou, Changhong C; Zhou, Danyan D; Ou, Xiaohua X; Xu, Yanyan Y; Tang, Yuanxiao Y; Ou, Xiaoyong X; Hu, Changming C; Ding, Xiangdong X; Luo, Pifu P; Yu, Shihui S

Publication Date: 2021

Variant appearance in text: EGFR: L833V

PubMed Link: 34257561

Variant Present in the following documents:

• Main text
• pore-27-602726.pdf

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Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma.

Cancer Immunology, Immunotherapy : Cii

Budczies, Jan J; Kirchner, Martina M; Kluck, Klaus K; Kazdal, Daniel D; Glade, Julia J; Allgäuer, Michael M; Kriegsmann, Mark M; Heußel, Claus-Peter CP; Herth, Felix J FJ; Winter, Hauke H; Meister, Michael M; Muley, Thomas T; Goldmann, Torsten T; Fröhling, Stefan S; Wermke, Martin M; Waller, Cornelius F CF; Tufman, Amanda A; Reck, Martin M; Peters, Solange S; Schirmacher, Peter P; Thomas, Michael M; Christopoulos, Petros P; Stenzinger, Albrecht A

Publication Date: 2021-06-14

Variant appearance in text: EGFR: Leu833Val

PubMed Link: 34125345

Variant Present in the following documents:

• 262_2021_2981_MOESM1_ESM.pdf

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Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma.

Cancer Immunology, Immunotherapy : Cii

Budczies, Jan J; Kirchner, Martina M; Kluck, Klaus K; Kazdal, Daniel D; Glade, Julia J; Allgäuer, Michael M; Kriegsmann, Mark M; Heußel, Claus-Peter CP; Herth, Felix J FJ; Winter, Hauke H; Meister, Michael M; Muley, Thomas T; Goldmann, Torsten T; Fröhling, Stefan S; Wermke, Martin M; Waller, Cornelius F CF; Tufman, Amanda A; Reck, Martin M; Peters, Solange S; Schirmacher, Peter P; Thomas, Michael M; Christopoulos, Petros P; Stenzinger, Albrecht A

Publication Date: 2022-02

Variant appearance in text: EGFR: Leu833Val

PubMed Link: 34125345

Variant Present in the following documents:

• 262_2021_2981_MOESM1_ESM.pdf

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Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Breast Cancer Research And Treatment

Nteliopoulos, Georgios G; Page, Karen K; Hills, Allison A; Howarth, Karen K; Emmett, Warren W; Green, Emma E; Martinson, Luke J LJ; Fernadez-Garcia, Daniel D; Hastings, Robert R; Guttery, David S DS; Kenny, Laura L; Stebbing, Justin J; Cleator, Susan S; Rehman, Farah F; Gleason, Kelly L T KLT; Sanela, Andrijac A; Ion, Charlotte C; Rushton, Amelia J AJ; Rosenfeld, Nitzan N; Coombes, R Charles RC; Shaw, Jacqueline A JA

Publication Date: 2021-07

Variant appearance in text: EGFR: L833V

PubMed Link: 34097174

Variant Present in the following documents:

• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 1
• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 2

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Successful treatment of triple EGFR mutation T785A/L861Q/H297_E298 with afatinib.

Thoracic Cancer

Longo, Vito V; Catino, Annamaria A; Montrone, Michele M; Pizzutilo, Pamela P; Pesola, Francesco F; Marech, Ilaria I; Capone, Iolanda I; Prelaj, Arsela A; Galetta, Domenico D

Publication Date: 2021-07

Variant appearance in text: EGFR: L833V

PubMed Link: 34008923

Variant Present in the following documents:

• TCA-12-2031.pdf

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