EGFR c.2522G>A ;(p.R841K)

Variant ID: 7-55259464-G-A

NM_005228.3(EGFR):c.2522G>A;(p.R841K)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: EGFR: R841K
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Tyrosine Kinase Receptors in Oncology.

International Journal Of Molecular Sciences
Esteban-Villarrubia, Jorge J; Soto-Castillo, Juan José JJ; Pozas, Javier J; San Román-Gil, María M; Orejana-Martín, Inmaculada I; Torres-Jiménez, Javier J; Carrato, Alfredo A; Alonso-Gordoa, Teresa T; Molina-Cerrillo, Javier J
Publication Date: 2020-11-12

Variant appearance in text: EGFR: R841K
PubMed Link: 33198314
Variant Present in the following documents:
  • ijms-21-08529.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: EGFR: R841K
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: R841K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.

Cell Chemical Biology
Truong, Thu H TH; Ung, Peter Man-Un PM; Palde, Prakash B PB; Paulsen, Candice E CE; Schlessinger, Avner A; Carroll, Kate S KS
Publication Date: 2016-07-21

Variant appearance in text: EGFR: R841K
PubMed Link: 27427230
Variant Present in the following documents:
  • Main text
View BVdb publication page



ProKinO: a unified resource for mining the cancer kinome.

Human Mutation
McSkimming, Daniel Ian DI; Dastgheib, Shima S; Talevich, Eric E; Narayanan, Anish A; Katiyar, Samiksha S; Taylor, Susan S SS; Kochut, Krys K; Kannan, Natarajan N
Publication Date: 2015-02

Variant appearance in text: EGFR: R841K
PubMed Link: 25382819
Variant Present in the following documents:
  • Main text
  • humu0036-0175.pdf
View BVdb publication page



The energy landscape analysis of cancer mutations in protein kinases.

Plos One
Dixit, Anshuman A; Verkhivker, Gennady M GM
Publication Date: 2011

Variant appearance in text: EGFR: R841K
PubMed Link: 21998754
Variant Present in the following documents:
View BVdb publication page