Publications:

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: ERBB2: E321G

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: ERBB2: Glu321Gly

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test.

Cellular Oncology (Dordrecht)

Harada, Yohei Y; Sato, Akemi A; Araki, Mitsugu M; Matsumoto, Shigeyuki S; Isaka, Yuta Y; Sagae, Yukari Y; Abe, Tomonori T; Aoyagi, Yasuko Y; Sueoka, Eisaburo E; Okuno, Yasushi Y; Kimura, Shinya S; Sueoka-Aragane, Naoko N

Publication Date: 2022-02

Variant appearance in text: HER2: E321G

PubMed Link: 34997908

Variant Present in the following documents:

• Main text
• 13402_2021_656_MOESM1_ESM.pdf
• 13402_2021_Article_656.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ERBB2: E321G

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2-targeted therapies.

Clinical And Translational Medicine

Zhang, Cheng C; Chen, Zuhua Z; Chong, Xiaoyi X; Chen, Yang Y; Wang, Zhenghang Z; Yu, Ruoying R; Sun, Tingting T; Chen, Xiaoxi X; Shao, Yang Y; Zhang, Xiaotian X; Gao, Jing J; Shen, Lin L

Publication Date: 2020-12

Variant appearance in text: ERBB2: E321G

PubMed Link: 33377634

Variant Present in the following documents:

• Main text
• CTM2-10-e254.pdf

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ERBB2: E321G

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Biomolecules

Shin, Jung Won JW; Kim, Soohyun S; Ha, Suji S; Choi, Byungsan B; Kim, Seongyeong S; Im, Seock-Ah SA; Yoon, Tae-Young TY; Chung, Junho J

Publication Date: 2019-10-19

Variant appearance in text: HER2: E321G

PubMed Link: 31635022

Variant Present in the following documents:

• Main text
• biomolecules-09-00629.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ERBB2: E321G

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine

Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L

Publication Date: 2018-07-27

Variant appearance in text: ERBB2: E321G

PubMed Link: 30053901

Variant Present in the following documents:

• 13073_2018_564_MOESM2_ESM.xlsx, sheet 3

View BVdb publication page

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Longitudinal analysis of treatment-induced genomic alterations in gliomas.

Genome Medicine

Erson-Omay, E Zeynep EZ; Henegariu, Octavian O; Omay, S Bülent SB; Harmancı, Akdes Serin AS; Youngblood, Mark W MW; Mishra-Gorur, Ketu K; Li, Jie J; Özduman, Koray K; Carrión-Grant, Geneive G; Clark, Victoria E VE; Çağlar, Caner C; Bakırcıoğlu, Mehmet M; Pamir, M Necmettin MN; Tabar, Viviane V; Vortmeyer, Alexander O AO; Bilguvar, Kaya K; Yasuno, Katsuhito K; DeAngelis, Lisa M LM; Baehring, Joachim M JM; Moliterno, Jennifer J; Günel, Murat M

Publication Date: 2017-02-02

Variant appearance in text: ERBB2: E321G

PubMed Link: 28153049

Variant Present in the following documents:

• 13073_2017_401_MOESM3_ESM.xlsx, sheet 2

View BVdb publication page

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Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology

Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP

Publication Date: 2015-03

Variant appearance in text: ERBB2: E321G

PubMed Link: 25794154

Variant Present in the following documents:

• pcbi.1004147.s001.xlsx, sheet 1

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: ERBB2: E321G

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib.

Cancer Biology & Therapy

de Martino, Michela M; Zhuang, Dazhong D; Klatte, Tobias T; Rieken, Malte M; Rouprêt, Morgan M; Xylinas, Evanguelos E; Clozel, Thomas T; Krzywinski, Martin M; Elemento, Olivier O; Shariat, Shahrokh F SF

Publication Date: 2014-09

Variant appearance in text: ERBB2: E321G

PubMed Link: 24971884

Variant Present in the following documents:

• Main text

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Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Greulich, Heidi H; Kaplan, Bethany B; Mertins, Philipp P; Chen, Tzu-Hsiu TH; Tanaka, Kumiko E KE; Yun, Cai-Hong CH; Zhang, Xiaohong X; Lee, Se-Hoon SH; Cho, Jeonghee J; Ambrogio, Lauren L; Liao, Rachel R; Imielinski, Marcin M; Banerji, Shantanu S; Berger, Alice H AH; Lawrence, Michael S MS; Zhang, Jinghui J; Pho, Nam H NH; Walker, Sarah R SR; Winckler, Wendy W; Getz, Gad G; Frank, David D; Hahn, William C WC; Eck, Michael J MJ; Mani, D R DR; Jaffe, Jacob D JD; Carr, Steven A SA; Wong, Kwok-Kin KK; Meyerson, Matthew M

Publication Date: 2012-09-04

Variant appearance in text: ERBB2: E321G

PubMed Link: 22908275

Variant Present in the following documents:

• Main text

View BVdb publication page

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