Publications:

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: ERBB2: D845A

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1

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Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test.

Cellular Oncology (Dordrecht)

Harada, Yohei Y; Sato, Akemi A; Araki, Mitsugu M; Matsumoto, Shigeyuki S; Isaka, Yuta Y; Sagae, Yukari Y; Abe, Tomonori T; Aoyagi, Yasuko Y; Sueoka, Eisaburo E; Okuno, Yasushi Y; Kimura, Shinya S; Sueoka-Aragane, Naoko N

Publication Date: 2022-02

Variant appearance in text: ERBB2: D845A

PubMed Link: 34997908

Variant Present in the following documents:

• Main text
• 13402_2021_Article_656.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ERBB2: D845A

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Regulation of Beclin 1-Mediated Autophagy by Oncogenic Tyrosine Kinases.

International Journal Of Molecular Sciences

Vega-Rubín-de-Celis, Silvia S; Kinch, Lisa L; Peña-Llopis, Samuel S

Publication Date: 2020-12-03

Variant appearance in text: HER2: D845A

PubMed Link: 33287140

Variant Present in the following documents:

• Main text
• ijms-21-09210.pdf

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ERBB2: D845A

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: ERBB2: 2534A>C; D845A

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ERBB2: D845A

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Increased autophagy blocks HER2-mediated breast tumorigenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Vega-Rubín-de-Celis, Silvia S; Zou, Zhongju Z; Fernández, Álvaro F ÁF; Ci, Bo B; Kim, Min M; Xiao, Guanghua G; Xie, Yang Y; Levine, Beth B

Publication Date: 2018-04-17

Variant appearance in text: HER2: D845A

PubMed Link: 29610308

Variant Present in the following documents:

• Main text
• pnas.201717800SI.pdf
• pnas.201717800.pdf

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HER2 as a target in invasive urothelial carcinoma.

Cancer Medicine

Bellmunt, Joaquim J; Werner, Lillian L; Bamias, Aristotle A; Fay, André P AP; Park, Rachel S RS; Riester, Markus M; Selvarajah, Shamini S; Barletta, Justine A JA; Berman, David M DM; de Muga, Silvia S; Salido, Marta M; Gallardo, Enrique E; Rojo, Federico F; Guancial, Elizabeth A EA; Bambury, Richard R; Mullane, Stephanie A SA; Choueiri, Toni K TK; Loda, Massimo M; Stack, Edward E; Rosenberg, Jonathan J

Publication Date: 2015-06

Variant appearance in text: HER2: D845A

PubMed Link: 25720673

Variant Present in the following documents:

• Main text
• cam40004-0844.pdf

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: ERBB2: D845A

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Greulich, Heidi H; Kaplan, Bethany B; Mertins, Philipp P; Chen, Tzu-Hsiu TH; Tanaka, Kumiko E KE; Yun, Cai-Hong CH; Zhang, Xiaohong X; Lee, Se-Hoon SH; Cho, Jeonghee J; Ambrogio, Lauren L; Liao, Rachel R; Imielinski, Marcin M; Banerji, Shantanu S; Berger, Alice H AH; Lawrence, Michael S MS; Zhang, Jinghui J; Pho, Nam H NH; Walker, Sarah R SR; Winckler, Wendy W; Getz, Gad G; Frank, David D; Hahn, William C WC; Eck, Michael J MJ; Mani, D R DR; Jaffe, Jacob D JD; Carr, Steven A SA; Wong, Kwok-Kin KK; Meyerson, Matthew M

Publication Date: 2012-09-04

Variant appearance in text: ERBB2: D845A

PubMed Link: 22908275

Variant Present in the following documents:

• Main text

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