Publications:

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Evaluation of Blood Tumor Mutation Burden for the Efficacy of Second-Line Atezolizumab Treatment in Non-Small Cell Lung Cancer: BUDDY Trial.

Cells

Park, Cheol-Kyu CK; Jun, Ha Ra HR; Oh, Hyung-Joo HJ; Lee, Ji-Young JY; Cho, Hyun-Ju HJ; Kim, Young-Chul YC; Lee, Jeong Eun JE; Yoon, Seong Hoon SH; Choi, Chang Min CM; Lee, Jae Cheol JC; Lee, Sung Yong SY; Lee, Shin Yup SY; Chun, Sung-Min SM; Oh, In-Jae IJ

Publication Date: 2023-04-25

Variant appearance in text: EGFR: S784F

PubMed Link: 37174645

Variant Present in the following documents:

• Main text
• cells-12-01246.pdf

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: EGFR: S784F

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4
• Table3.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: EGFR: S784F

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: S784F

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

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Development and Validation of a Targeted 'Liquid' NGS Panel for Treatment Customization in Patients with Metastatic Colorectal Cancer.

Diagnostics (Basel, Switzerland)

Kastrisiou, Myrto M; Zarkavelis, George G; Kougioumtzi, Anastasia A; Sakaloglou, Prodromos P; Kostoulas, Charilaos C; Georgiou, Ioannis I; Batistatou, Anna A; Pentheroudakis, George G; Magklara, Angeliki A

Publication Date: 2021-12-16

Variant appearance in text: EGFR: S784F

PubMed Link: 34943612

Variant Present in the following documents:

• Main text
• diagnostics-11-02375.pdf

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Development and Validation of a Targeted 'Liquid' NGS Panel for Treatment Customization in Patients with Metastatic Colorectal Cancer.

Diagnostics (Basel, Switzerland)

Kastrisiou, Myrto M; Zarkavelis, George G; Kougioumtzi, Anastasia A; Sakaloglou, Prodromos P; Kostoulas, Charilaos C; Georgiou, Ioannis I; Batistatou, Anna A; Pentheroudakis, George G; Magklara, Angeliki A

Publication Date: 2021-12-16

Variant appearance in text: EGFR: S784F

PubMed Link: 34943612

Variant Present in the following documents:

• Main text
• diagnostics-11-02375.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: S784F

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature

Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV

Publication Date: 2021-09

Variant appearance in text: EGFR: 2351C>T

PubMed Link: 34526717

Variant Present in the following documents:

• 41586_2021_3898_MOESM1_ESM.pdf
• 41586_2021_Article_3898.pdf

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2351C>T; S784F

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Concurrent Genetic Alterations and Other Biomarkers Predict Treatment Efficacy of EGFR-TKIs in EGFR-Mutant Non-Small Cell Lung Cancer: A Review.

Frontiers In Oncology

Guo, Yijia Y; Song, Jun J; Wang, Yanru Y; Huang, Letian L; Sun, Li L; Zhao, Jianzhu J; Zhang, Shuling S; Jing, Wei W; Ma, Jietao J; Han, Chengbo C

Publication Date: 2020

Variant appearance in text: EGFR: S784F

PubMed Link: 33363040

Variant Present in the following documents:

• Main text
• fonc-10-610923.pdf

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: EGFR: S784F

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3

View BVdb publication page

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ErBb Family Proteins in Cholangiocarcinoma and Clinical Implications.

Journal Of Clinical Medicine

Jin, Wook W

Publication Date: 2020-07-16

Variant appearance in text: EGFR: S784F

PubMed Link: 32708604

Variant Present in the following documents:

• Main text
• jcm-09-02255.pdf

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New therapeutic approaches to overcoming resistant EGFR exon 20 alterations.

Critical Reviews In Oncology/Hematology

Li, Alex M AM; Boichard, Amélie A; Felip, Enriqueta E; Kurzrock, Razelle R

Publication Date: 2020-07

Variant appearance in text: EGFR: S784F

PubMed Link: 32485428

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: S784F

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: EGFR: S784F

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression.

Ebiomedicine

Mäki-Nevala, Satu S; Valo, Satu S; Ristimäki, Ari A; Sarhadi, Virinder V; Knuutila, Sakari S; Nyström, Minna M; Renkonen-Sinisalo, Laura L; Lepistö, Anna A; Mecklin, Jukka-Pekka JP; Peltomäki, Päivi P

Publication Date: 2019-01

Variant appearance in text: EGFR: Ser784Phe

PubMed Link: 30578081

Variant Present in the following documents:

• mmc1.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: S784F

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

View BVdb publication page

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Comparison of Epidermal Growth Factor Receptor Mutations between Metastatic Lymph Node Diagnosed by EBUS-TBNA and Primary Tumor in Non-Small Cell Lung Cancer.

Plos One

Kang, Hyo Jae HJ; Hwangbo, Bin B; Lee, Jin Soo JS; Kim, Moon Soo MS; Lee, Jong Mog JM; Lee, Geon-Kook GK

Publication Date: 2016

Variant appearance in text: EGFR: S784F

PubMed Link: 27685950

Variant Present in the following documents:

• Main text
• pone.0163652.pdf

View BVdb publication page

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Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016-01-18

Variant appearance in text: EGFR: 2351C>T

PubMed Link: 26782967

Variant Present in the following documents:

• 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology

Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP

Publication Date: 2015-03

Variant appearance in text: EGFR: S784F

PubMed Link: 25794154

Variant Present in the following documents:

• pcbi.1004147.s001.xlsx, sheet 1

View BVdb publication page

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: EGFR: S784F

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Yeh, Paul P; Chen, Heidi H; Andrews, Jenny J; Naser, Riyad R; Pao, William W; Horn, Leora L

Publication Date: 2013-04-01

Variant appearance in text: EGFR: S784F

PubMed Link: 23344264

Variant Present in the following documents:

• Main text

View BVdb publication page

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The energy landscape analysis of cancer mutations in protein kinases.

Plos One

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2011

Variant appearance in text: EGFR: S784F

PubMed Link: 21998754

Variant Present in the following documents:

View BVdb publication page

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: EGFR: S784F

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

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Co-conserved features associated with cis regulation of ErbB tyrosine kinases.

Plos One

Mirza, Amar A; Mustafa, Morad M; Talevich, Eric E; Kannan, Natarajan N

Publication Date: 2010-12-13

Variant appearance in text: EGFR: S784F

PubMed Link: 21179209

Variant Present in the following documents:

• Main text

View BVdb publication page

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Good Clinical Response to Erlotinib in a Non-Small Cell Lung Cancer Patient Harboring Multiple Brain Metastases and a Double Active Somatic Epidermal Growth Factor Gene Mutation.

Case Reports In Oncology

Masago, Katsuhiro K; Togashi, Yosuke Y; Fukudo, Masahide M; Terada, Tomohiro T; Irisa, Kaoru K; Sakamori, Yuichi Y; Fujita, Shiro S; Kim, Young Hak YH; Mio, Tadashi T; Inui, Ken-Ichi KI; Mishima, Michiaki M

Publication Date: 2010-04-22

Variant appearance in text: EGFR: S784F

PubMed Link: 20740181

Variant Present in the following documents:

• Main text
• cro0003-0098.pdf

View BVdb publication page

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