ERBB2 c.2570A>G ;(p.N857S)

Variant ID: 17-37881378-A-G

NM_004448.2(ERBB2):c.2570A>G;(p.N857S)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: ERBB2: N857S
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Targeted Sequencing of Taiwanese Breast Cancer with Risk Stratification by the Concurrent Genes Signature: A Feasibility Study.

Journal Of Personalized Medicine
Huang, Ching-Shui CS; Liu, Chih-Yi CY; Lu, Tzu-Pin TP; Huang, Chi-Jung CJ; Chiu, Jen-Hwey JH; Tseng, Ling-Ming LM; Huang, Chi-Cheng CC
Publication Date: 2021-06-28

Variant appearance in text: ERBB2: N857S; rs28933370
PubMed Link: 34203389
Variant Present in the following documents:
  • Main text
  • jpm-11-00613.pdf
View BVdb publication page



Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y
Publication Date: 2020-08-01

Variant appearance in text: ERBB2: N857S
PubMed Link: 32738923
Variant Present in the following documents:
  • 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: ERBB2: N857S
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Development and validation of a targeted gene sequencing panel for application to disparate cancers.

Scientific Reports
McCabe, Mark J MJ; Gauthier, Marie-Emilie A MA; Chan, Chia-Ling CL; Thompson, Tanya J TJ; De Sousa, Sunita M C SMC; Puttick, Clare C; Grady, John P JP; Gayevskiy, Velimir V; Tao, Jiang J; Ying, Kevin K; Cipponi, Arcadi A; Deng, Niantao N; Swarbrick, Alex A; Thomas, Melissa L ML; Lord, Reginald V RV; Johns, Amber L AL; Kohonen-Corish, Maija M; O'Toole, Sandra A SA; Clark, Jonathan J; Mueller, Simon A SA; Gupta, Ruta R; McCormack, Ann I AI; Dinger, Marcel E ME; Cowley, Mark J MJ; ,
Publication Date: 2019-11-19

Variant appearance in text: ERBB2: 2570A>G; N857S
PubMed Link: 31745186
Variant Present in the following documents:
  • 41598_2019_52000_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.

Frontiers In Molecular Biosciences
Dehghani, Mehdi M; Rosenblatt, Kevin P KP; Li, Lei L; Rakhade, Mrudula M; Amato, Robert J RJ
Publication Date: 2019

Variant appearance in text: ERBB2: Asn857Ser
PubMed Link: 31681791
Variant Present in the following documents:
  • Data_Sheet_5.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: ERBB2: N857S
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Validation of the Oncomineā„¢ focus panel for next-generation sequencing of clinical tumour samples.

Virchows Archiv : An International Journal Of Pathology
Williams, Hannah L HL; Walsh, Kathy K; Diamond, Austin A; Oniscu, Anca A; Deans, Zandra C ZC
Publication Date: 2018-10

Variant appearance in text: ERBB2: 2570A>G; N857S
PubMed Link: 30105577
Variant Present in the following documents:
  • 428_2018_2411_MOESM1_ESM.xlsx, sheet 3
  • 428_2018_2411_MOESM1_ESM.xlsx, sheet 4
  • 428_2018_2411_MOESM4_ESM.xlsx, sheet 1
  • 428_2018_2411_MOESM3_ESM.xlsx, sheet 1
  • 428_2018_2411_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Mobile Genome Express (MGE): A comprehensive automatic genetic analyses pipeline with a mobile device.

Plos One
Yoon, Jun-Hee JH; Kim, Thomas W TW; Mendez, Pedro P; Jablons, David M DM; Kim, Il-Jin IJ
Publication Date: 2017

Variant appearance in text: ERBB2: 2570A>G; N857S
PubMed Link: 28403238
Variant Present in the following documents:
  • pone.0174696.pdf
View BVdb publication page



One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

Elife
Gudernova, Iva I; Foldynova-Trantirkova, Silvie S; Ghannamova, Barbora El BE; Fafilek, Bohumil B; Varecha, Miroslav M; Balek, Lukas L; Hruba, Eva E; Jonatova, Lucie L; Jelinkova, Iva I; Kunova Bosakova, Michaela M; Trantirek, Lukas L; Mayer, Jiri J; Krejci, Pavel P
Publication Date: 2017-02-15

Variant appearance in text: ERBB2: N857S
PubMed Link: 28199182
Variant Present in the following documents:
  • elife-21536-supp3.xlsx, sheet 1
  • elife-21536-supp3.xlsx, sheet 2
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs28933370
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: ERBB2: N857S
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



CanDrA: cancer-specific driver missense mutation annotation with optimized features.

Plos One
Mao, Yong Y; Chen, Han H; Liang, Han H; Meric-Bernstam, Funda F; Mills, Gordon B GB; Chen, Ken K
Publication Date: 2013

Variant appearance in text: ERBB2: N857S
PubMed Link: 24205039
Variant Present in the following documents:
  • pone.0077945.s001.xls, sheet 5
  • pone.0077945.s001.xls, sheet 4
View BVdb publication page



Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib.

Plos One
Kancha, Rama Krishna RK; von Bubnoff, Nikolas N; Bartosch, Natalie N; Peschel, Christian C; Engh, Richard A RA; Duyster, Justus J
Publication Date: 2011

Variant appearance in text: ERBB2: N857S
PubMed Link: 22046346
Variant Present in the following documents:
  • Main text
  • pone.0026760.pdf
View BVdb publication page



A growing family: adding mutated Erbb4 as a novel cancer target.

Cell Cycle (Georgetown, Tex.)
Rudloff, Udo U; Samuels, Yardena Y
Publication Date: 2010-04-15

Variant appearance in text: ERBB2: N857S
PubMed Link: 20404484
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

Nature Genetics
Prickett, Todd D TD; Agrawal, Neena S NS; Wei, Xiaomu X; Yates, Kristin E KE; Lin, Jimmy C JC; Wunderlich, John R JR; Cronin, Julia C JC; Cruz, Pedro P; Rosenberg, Steven A SA; Samuels, Yardena Y
Publication Date: 2009-10

Variant appearance in text: ERBB2: N857S
PubMed Link: 19718025
Variant Present in the following documents:
  • Main text
View BVdb publication page