Publications:

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Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer.

Breast Cancer Research And Treatment

Bos, M K MK; Lam, S W SW; Motta, G G; Helmijr, J C A JCA; Beaufort, C M CM; de Jonge, E E; Martens, J W M JWM; Boven, E E; Jansen, M P H M MPHM; Jager, A A; Sleijfer, S S

Publication Date: 2023-05-25

Variant appearance in text: ESR1: S463P

PubMed Link: 37226020

Variant Present in the following documents:

• Main text
• 10549_2023_Article_6965.pdf

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Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine

Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA

Publication Date: 2023-01-17

Variant appearance in text: ESR1: S463P

PubMed Link: 36652909

Variant Present in the following documents:

• mmc8.xlsx, sheet 11
• mmc3.xlsx, sheet 12

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The Clinical Utility of Droplet Digital PCR for Profiling Circulating Tumor DNA in Breast Cancer Patients.

Diagnostics (Basel, Switzerland)

Gezer, Ugur U; Bronkhorst, Abel J AJ; Holdenrieder, Stefan S

Publication Date: 2022-12-05

Variant appearance in text: ESR1: S463P

PubMed Link: 36553049

Variant Present in the following documents:

• Main text
• diagnostics-12-03042.pdf

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.

Nature Communications

Sivakumar, Smruthy S; Jin, Dexter X DX; Tukachinsky, Hanna H; Murugesan, Karthikeyan K; McGregor, Kimberly K; Danziger, Natalie N; Pavlick, Dean D; Gjoerup, Ole O; Ross, Jeffrey S JS; Harmon, Robert R; Chung, Jon J; Decker, Brennan B; Dennis, Lucas L; Frampton, Garrett M GM; Molinero, Luciana L; Oesterreich, Steffi S; Venstrom, Jeffrey M JM; Oxnard, Geoffrey R GR; Hegde, Priti S PS; Sokol, Ethan S ES

Publication Date: 2022-12-05

Variant appearance in text: ESR1: S463P

PubMed Link: 36470901

Variant Present in the following documents:

• 41467_2022_35245_MOESM4_ESM.xlsx, sheet 17

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The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 -) advanced/metastatic breast cancer.

Breast Cancer Research And Treatment

Bardia, Aditya A; Mayer, Ingrid I; Winer, Eric E; Linden, Hannah M HM; Ma, Cynthia X CX; Parker, Barbara A BA; Bellet, Meritxell M; Arteaga, Carlos L CL; Cheeti, Sravanthi S; Gates, Mary M; Chang, Ching-Wei CW; Fredrickson, Jill J; Spoerke, Jill M JM; Moore, Heather M HM; Giltnane, Jennifer J; Friedman, Lori S LS; Chow Maneval, Edna E; Chan, Iris I; Jhaveri, Komal K

Publication Date: 2022-11-19

Variant appearance in text: ESR1: S463P

PubMed Link: 36401732

Variant Present in the following documents:

• 10549_2022_6797_MOESM1_ESM.pdf

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: ESR1: 1387T>C; S463P

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer.

British Journal Of Cancer

Fernandez-Garcia, Daniel D; Nteliopoulos, Georgios G; Hastings, Robert K RK; Rushton, Amelia A; Page, Karen K; Allsopp, Rebecca C RC; Ambasager, Bana B; Gleason, Kelly K; Guttery, David S DS; Ali, Simak S; Charles Coombes, R R; Shaw, Jacqueline A JA

Publication Date: 2022-11

Variant appearance in text: ESR1: S463P

PubMed Link: 36088510

Variant Present in the following documents:

• 41416_2022_1962_MOESM2_ESM.xlsx, sheet 5
• 41416_2022_1962_MOESM2_ESM.xlsx, sheet 4

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Predictors of fulvestrant long-term benefit in hormone receptor-positive/HER2 negative advanced breast cancer.

Scientific Reports

Torrisi, Rosalba R; Vaira, Valentina V; Giordano, Laura L; Destro, Annarita A; Basilico, Vera V; Mazzara, Saveria S; Salvini, Piermario P; Gaudioso, Gabriella G; Fernandes, Bethania B; Rudini, Noemi N; Masci, Giovanna G; Santoro, Armando A

Publication Date: 2022-07-27

Variant appearance in text: ESR1: S463P

PubMed Link: 35896637

Variant Present in the following documents:

• Main text
• 41598_2022_Article_16409.pdf
• 41598_2022_16409_MOESM1_ESM.xlsx, sheet 1

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AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer.

Nature Communications

Bardia, Aditya A; Chandarlapaty, Sarat S; Linden, Hannah M HM; Ulaner, Gary A GA; Gosselin, Alice A; Cartot-Cotton, Sylvaine S; Cohen, Patrick P; Doroumian, Séverine S; Paux, Gautier G; Celanovic, Marina M; Pelekanou, Vasiliki V; Ming, Jeffrey E JE; Ternès, Nils N; Bouaboula, Monsif M; Lee, Joon Sang JS; Bauchet, Anne-Laure AL; Campone, Mario M

Publication Date: 2022-07-15

Variant appearance in text: ESR1: S463P

PubMed Link: 35840573

Variant Present in the following documents:

• Main text
• 41467_2022_Article_31668.pdf

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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: ESR1: S463P

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

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Estrogen Receptor Bio-Activities Determine Clinical Endocrine Treatment Options in Estrogen Receptor-Positive Breast Cancer.

Technology In Cancer Research & Treatment

Xia, Song S; Lin, Qiong Q

Publication Date: 2022

Variant appearance in text: ESR1: S463P

PubMed Link: 35450488

Variant Present in the following documents:

• Main text
• 10.1177_15330338221090351.pdf

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: ESR1: 1387T>C; S463P

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

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Role of ctDNA in Breast Cancer.

Cancers

Sant, Marta M; Bernat-Peguera, Adrià A; Felip, Eudald E; Margelí, Mireia M

Publication Date: 2022-01-09

Variant appearance in text: ESR1: S463P

PubMed Link: 35053474

Variant Present in the following documents:

• Main text
• cancers-14-00310.pdf

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Role of ctDNA in Breast Cancer.

Cancers

Sant, Marta M; Bernat-Peguera, Adrià A; Felip, Eudald E; Margelí, Mireia M

Publication Date: 2022-01-09

Variant appearance in text: ESR1: S463P

PubMed Link: 35053474

Variant Present in the following documents:

• Main text
• cancers-14-00310.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ESR1: S463P

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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A review of the endocrine resistance in hormone-positive breast cancer.

American Journal Of Cancer Research

Chien, Tsai-Ju TJ

Publication Date: 2021

Variant appearance in text: ESR1: S463P

PubMed Link: 34522451

Variant Present in the following documents:

• Main text

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: ESR1: S463P

PubMed Link: 34440110

Variant Present in the following documents:

• Main text

View BVdb publication page

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ESR1 mutation as an emerging clinical biomarker in metastatic hormone receptor-positive breast cancer.

Breast Cancer Research : Bcr

Brett, Jamie O JO; Spring, Laura M LM; Bardia, Aditya A; Wander, Seth A SA

Publication Date: 2021-08-15

Variant appearance in text: ESR1: S463P

PubMed Link: 34392831

Variant Present in the following documents:

• Main text
• 13058_2021_Article_1462.pdf

View BVdb publication page

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Estrogen receptor-α signaling in post-natal mammary development and breast cancers.

Cellular And Molecular Life Sciences : Cmls

Rusidzé, Mariam M; Adlanmérini, Marine M; Chantalat, Elodie E; Raymond-Letron, I I; Cayre, Surya S; Arnal, Jean-François JF; Deugnier, Marie-Ange MA; Lenfant, Françoise F

Publication Date: 2021-08

Variant appearance in text: ESR1: S463P

PubMed Link: 34156490

Variant Present in the following documents:

• Main text

View BVdb publication page

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Longitudinal Dynamics of Circulating Tumor Cells and Circulating Tumor DNA for Treatment Monitoring in Metastatic Breast Cancer.

Jco Precision Oncology

Gerratana, Lorenzo L; Davis, Andrew A AA; Zhang, Qiang Q; Basile, Debora D; Rossi, Giovanna G; Strickland, Kimberly K; Franzoni, Alessandra A; Allegri, Lorenzo L; Mu, Zhaomei Z; Zhang, Youbin Y; Flaum, Lisa E LE; Damante, Giuseppe G; Gradishar, William John WJ; Platanias, Leonidas C LC; Behdad, Amir A; Yang, Hushan H; Puglisi, Fabio F; Cristofanilli, Massimo M

Publication Date: 2021-06

Variant appearance in text: ESR1: S463P

PubMed Link: 34136741

Variant Present in the following documents:

• po-5-943.pdf

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Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer.

Jnci Cancer Spectrum

Dahlgren, Malin M; George, Anthony M AM; Brueffer, Christian C; Gladchuk, Sergii S; Chen, Yilun Y; Vallon-Christersson, Johan J; Hegardt, Cecilia C; Häkkinen, Jari J; Rydén, Lisa L; Malmberg, Martin M; Larsson, Christer C; Gruvberger-Saal, Sofia K SK; Ehinger, Anna A; Loman, Niklas N; Borg, Åke Å; Saal, Lao H LH

Publication Date: 2021-04

Variant appearance in text: ESR1: S463P

PubMed Link: 33937624

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular Biomarkers for Contemporary Therapies in Hormone Receptor-Positive Breast Cancer.

Genes

Freelander, Allegra A; Brown, Lauren J LJ; Parker, Andrew A; Segara, Davendra D; Portman, Neil N; Lau, Brandon B; Lim, Elgene E

Publication Date: 2021-02-17

Variant appearance in text: ESR1: Ser463Pro

PubMed Link: 33671468

Variant Present in the following documents:

• Main text
• genes-12-00285.pdf

View BVdb publication page

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: ESR1: S463P

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

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Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.

Plos One

Akolkar, Dadasaheb D; Patil, Darshana D; Srivastava, Navin N; Patil, Revati R; Datta, Vineet V; Apurwa, Sachin S; Yashwante, Nitin N; Dhasarathan, Raja R; Gosavi, Rahul R; John, Jinumary J; Khan, Shabishta S; Jadhav, Ninad N; Mene, Priti P; Ahire, Dhanashri D; Pawar, Sushant S; Bodke, Harshal H; Sahoo, Subhraline S; Nile, Arun A; Saindane, Dinesh D; Darokar, Harshal H; Devhare, Pradip P; Srinivasan, Ajay A; Datar, Rajan R

Publication Date: 2021

Variant appearance in text: ESR1: S463P

PubMed Link: 33556149

Variant Present in the following documents:

• pone.0246048.s008.xlsx, sheet 1

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A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses.

International Journal Of Molecular Sciences

Clusan, Léa L; Le Goff, Pascale P; Flouriot, Gilles G; Pakdel, Farzad F

Publication Date: 2021-01-13

Variant appearance in text: ESR1: S463P

PubMed Link: 33451133

Variant Present in the following documents:

• Main text
• ijms-22-00756.pdf

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: ESR1: 1387T>C; S463P

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: ESR1: S463P

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1
• CAM4-10-53-s002.xlsx, sheet 1

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Currently Applied Molecular Assays for Identifying ESR1 Mutations in Patients with Advanced Breast Cancer.

International Journal Of Molecular Sciences

Lee, Nuri N; Park, Min-Jeong MJ; Song, Wonkeun W; Jeon, Kibum K; Jeong, Seri S

Publication Date: 2020-11-20

Variant appearance in text: ESR1: S463P

PubMed Link: 33233830

Variant Present in the following documents:

• Main text
• ijms-21-08807.pdf

View BVdb publication page

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

Variant appearance in text: ESR1: 1387T>C; S463P

PubMed Link: 33145402

Variant Present in the following documents:

• 41523_2020_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs1057519714

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial.

The Lancet. Oncology

Turner, Nicholas C NC; Kingston, Belinda B; Kilburn, Lucy S LS; Kernaghan, Sarah S; Wardley, Andrew M AM; Macpherson, Iain R IR; Baird, Richard D RD; Roylance, Rebecca R; Stephens, Peter P; Oikonomidou, Olga O; Braybrooke, Jeremy P JP; Tuthill, Mark M; Abraham, Jacinta J; Winter, Matthew C MC; Bye, Hannah H; Hubank, Michael M; Gevensleben, Heidrun H; Cutts, Ros R; Snowdon, Claire C; Rea, Daniel D; Cameron, David D; Shaaban, Abeer A; Randle, Katrina K; Martin, Sue S; Wilkinson, Katie K; Moretti, Laura L; Bliss, Judith M JM; Ring, Alistair A

Publication Date: 2020-10

Variant appearance in text: ESR1: 1387T>C; S463P

PubMed Link: 32919527

Variant Present in the following documents:

• mmc1.pdf

View BVdb publication page

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A phase 1b study evaluating the effect of elacestrant treatment on estrogen receptor availability and estradiol binding to the estrogen receptor in metastatic breast cancer lesions using 18F-FES PET/CT imaging.

Breast Cancer Research : Bcr

Jager, Agnes A; de Vries, Elisabeth G E EGE; der Houven van Oordt, C Willemien Menke-van CWM; Neven, Patrick P; Venema, Clasina M CM; Glaudemans, Andor W J M AWJM; Wang, Yamei Y; Bagley, Rebecca G RG; Conlan, Maureen G MG; Aftimos, Philippe P

Publication Date: 2020-09-11

Variant appearance in text: ESR1: S463P

PubMed Link: 32912274

Variant Present in the following documents:

• Main text

View BVdb publication page

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Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.

Science Advances

Lee, Sangsin S; Ding, Ning N; Sun, Yidi Y; Yuan, Tanglong T; Li, Jing J; Yuan, Qichen Q; Liu, Lizhong L; Yang, Jie J; Wang, Qian Q; Kolomeisky, Anatoly B AB; Hilton, Isaac B IB; Zuo, Erwei E; Gao, Xue X

Publication Date: 2020-07

Variant appearance in text: ESR1: 1387T>C; Ser463Pro

PubMed Link: 32832622

Variant Present in the following documents:

• aba1773_Data_file_S1.xlsx, sheet 2

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: ESR1: S463P

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Advances in the Detection Technologies and Clinical Applications of Circulating Tumor DNA in Metastatic Breast Cancer.

Cancer Management And Research

Liao, Hao H; Li, Huiping H

Publication Date: 2020

Variant appearance in text: ESR1: S463P

PubMed Link: 32547192

Variant Present in the following documents:

• Main text

View BVdb publication page

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Risk of early progression according to circulating ESR1 mutation, CA-15.3 and cfDNA increases under first-line anti-aromatase treatment in metastatic breast cancer.

Breast Cancer Research : Bcr

Clatot, Florian F; Perdrix, Anne A; Beaussire, Ludivine L; Lequesne, Justine J; Lévy, Christelle C; Emile, George G; Bubenheim, Michael M; Lacaille, Sigrid S; Calbrix, Céline C; Augusto, Laetitia L; Guillemet, Cécile C; Alexandru, Cristina C; Fontanilles, Maxime M; Sefrioui, David D; Burel, Lucie L; Guénot, Sabine S; Richard, Doriane D; Sarafan-Vasseur, Nasrin N; Di Fiore, Frédéric F

Publication Date: 2020-05-28

Variant appearance in text: ESR1: S463P

PubMed Link: 32466779

Variant Present in the following documents:

• Main text
• 13058_2020_Article_1290.pdf

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Quantitative Evaluation of the Transcriptional Activity of Steroid Hormone Receptor Mutants and Variants Using a Single Vector With Two Reporters and a Receptor Expression Cassette.

Frontiers In Endocrinology

Ji, Huimin H; Li, Ying Y; Liu, Zhao Z; Tang, Min M; Zou, Lihui L; Su, Fei F; Zhang, Yaqun Y; Zhang, Junhua J; Li, Hexin H; Li, Lin L; Ai, Bin B; Ma, Jie J; Wang, Lunan L; Liu, Ming M; Xiao, Fei F

Publication Date: 2020

Variant appearance in text: ESR1: S463P

PubMed Link: 32296391

Variant Present in the following documents:

• fendo-11-00167.pdf

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OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine.

Scientific Reports

López-Cortés, Andrés A; Paz-Y-Miño, César C; Guerrero, Santiago S; Cabrera-Andrade, Alejandro A; Barigye, Stephen J SJ; Munteanu, Cristian R CR; González-Díaz, Humberto H; Pazos, Alejandro A; Pérez-Castillo, Yunierkis Y; Tejera, Eduardo E

Publication Date: 2020-03-24

Variant appearance in text: ESR1: S463P

PubMed Link: 32210335

Variant Present in the following documents:

• 41598_2020_62279_MOESM2_ESM.xlsx, sheet 33

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ESR1: S463P

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer.

Translational Oncology

Masunaga, Nanae N; Kagara, Naofumi N; Motooka, Daisuke D; Nakamura, Shota S; Miyake, Tomohiro T; Tanei, Tomonori T; Naoi, Yasuto Y; Shimoda, Masafumi M; Shimazu, Kenzo K; Kim, Seung Jin SJ; Noguchi, Shinzaburo S

Publication Date: 2020-03

Variant appearance in text: ESR1: S463P

PubMed Link: 32105989

Variant Present in the following documents:

• Main text

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Dynamics Insights Into the Gain of Flexibility by Helix-12 in ESR1 as a Mechanism of Resistance to Drugs in Breast Cancer Cell Lines.

Frontiers In Molecular Biosciences

Khan, Abbas A; Ashfaq-Ur-Rehman, ; Junaid, Muhammad M; Li, Cheng-Dong CD; Saleem, Shoaib S; Humayun, Fahad F; Shamas, Shazia S; Ali, Syed Shujait SS; Babar, Zainib Z; Wei, Dong-Qing DQ

Publication Date: 2019

Variant appearance in text: ESR1: S463P

PubMed Link: 32039233

Variant Present in the following documents:

• Main text
• fmolb-06-00159.pdf

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Prevalence of ESR1 Mutation in Chinese ER-Positive Breast Cancer.

Oncotargets And Therapy

Zhu, Wenzhen W; Ren, Chongyang C; Wang, Yulei Y; Wen, Lingzhu L; Zhang, Guochun G; Liao, Ning N

Publication Date: 2020

Variant appearance in text: ESR1: S463P

PubMed Link: 32021303

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• Main text

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ESR1 mutations in breast cancer.

Cancer

Dustin, Derek D; Gu, Guowei G; Fuqua, Suzanne A W SAW

Publication Date: 2019-11-01

Variant appearance in text: ESR1: S463P

PubMed Link: 31318440

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Endocrine and Targeted Therapy for Hormone-Receptor-Positive, HER2-Negative Advanced Breast Cancer: Insights to Sequencing Treatment and Overcoming Resistance Based on Clinical Trials.

Frontiers In Oncology

El Sayed, Rola R; El Jamal, Lara L; El Iskandarani, Sarah S; Kort, Jeries J; Abdel Salam, Mahmoud M; Assi, Hazem H

Publication Date: 2019

Variant appearance in text: ESR1: S463P

PubMed Link: 31281796

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ESR1 alterations and metastasis in estrogen receptor positive breast cancer.

Journal Of Cancer Metastasis And Treatment

Lei, Jonathan T JT; Gou, Xuxu X; Seker, Sinem S; Ellis, Matthew J MJ

Publication Date: 2019

Variant appearance in text: ESR1: S463P

PubMed Link: 31106278

Variant Present in the following documents:

• Main text
• nihms-1027703.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ESR1: S463P

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Genomic Comparison of Endometrioid Endometrial Carcinoma and Its Precancerous Lesions in Chinese Patients by High-Depth Next Generation Sequencing.

Frontiers In Oncology

Wang, Yao Y; Yu, Mei M; Yang, Jia-Xin JX; Cao, Dong-Yan DY; Zhang, Ying Y; Zhou, Hui-Mei HM; Yuan, Zhen Z; Shen, Keng K

Publication Date: 2019

Variant appearance in text: ESR1: 1387T>C; S463P

PubMed Link: 30886832

Variant Present in the following documents:

• Table_2.xls, sheet 2
• Table_2.xls, sheet 1

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ESR1 mutations in metastatic lobular breast cancer patients.

Npj Breast Cancer

Desmedt, Christine C; Pingitore, Julien J; Rothé, Françoise F; Marchio, Caterina C; Clatot, Florian F; Rouas, Ghizlane G; Richard, François F; Bertucci, François F; Mariani, Odette O; Galant, Christine C; Fribbens, Charlotte C; O'Leary, Ben B; van den Eynden, Gert G; Salgado, Roberto R; Turner, Nicholas C NC; Piccart, Martine M; Vincent-Salomon, Anne A; Pruneri, Giancarlo G; Larsimont, Denis D; Sotiriou, Christos C

Publication Date: 2019

Variant appearance in text: ESR1: S463P

PubMed Link: 30820448

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• Main text
• 41523_2019_Article_104.pdf

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Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Research : Bcr

Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV

Publication Date: 2019-02-08

Variant appearance in text: ESR1: S463P

PubMed Link: 30736836

Variant Present in the following documents:

• 13058_2019_1102_MOESM2_ESM.xlsx, sheet 1

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