Publications:

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Development and validation of a mutation-based model to predict immunotherapeutic efficacy in NSCLC.

Frontiers In Oncology

He, Ping P; Liu, Jie J; Xu, Qingyuan Q; Ma, Huaijun H; Niu, Beifang B; Huang, Gang G; Wu, Wei W

Publication Date: 2023

Variant appearance in text: EGFR: 2492G>A; R831H; rs150036236

PubMed Link: 36910641

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 8

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: EGFR: 2492G>A; Arg831His

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Clinicopathologic features of gastric glomus tumor: A report of 15 cases and literature review.

Pathology Oncology Research : Por

Deng, Minying M; Luo, Rongkui R; Huang, Jie J; Luo, Yuanlong Y; Song, Qi Q; Liang, Huaiyu H; Xu, Chen C; Yuan, Wei W; Hou, Yingyong Y

Publication Date: 2022

Variant appearance in text: EGFR: R831H

PubMed Link: 36699621

Variant Present in the following documents:

• Main text
• pore-28-1610824.pdf

View BVdb publication page

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The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.

Nature Cancer

Villani, Anita A; Davidson, Scott S; Kanwar, Nisha N; Lo, Winnie W WW; Li, Yisu Y; Cohen-Gogo, Sarah S; Fuligni, Fabio F; Edward, Lisa-Monique LM; Light, Nicholas N; Layeghifard, Mehdi M; Harripaul, Ricardo R; Waldman, Larissa L; Gallinger, Bailey B; Comitani, Federico F; Brunga, Ledia L; Hayes, Reid R; Anderson, Nathaniel D ND; Ramani, Arun K AK; Yuki, Kyoko E KE; Blay, Sasha S; Johnstone, Brittney B; Inglese, Cara C; Hammad, Rawan R; Goudie, Catherine C; Shuen, Andrew A; Wasserman, Jonathan D JD; Venier, Rosemarie E RE; Eliou, Marianne M; Lorenti, Miranda M; Ryan, Carol Ann CA; Braga, Michael M; Gloven-Brown, Meagan M; Han, Jianan J; Montero, Maria M; Spatare, Famida F; Whitlock, James A JA; Scherer, Stephen W SW; Chun, Kathy K; Somerville, Martin J MJ; Hawkins, Cynthia C; Abdelhaleem, Mohamed M; Ramaswamy, Vijay V; Somers, Gino R GR; Kyriakopoulou, Lianna L; Hitzler, Johann J; Shago, Mary M; Morgenstern, Daniel A DA; Tabori, Uri U; Meyn, Stephen S; Irwin, Meredith S MS; Malkin, David D; Shlien, Adam A

Publication Date: 2022-12-30

Variant appearance in text: EGFR: R831H

PubMed Link: 36585449

Variant Present in the following documents:

• 43018_2022_474_MOESM7_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM12_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM12_ESM.xlsx, sheet 7
• 43018_2022_474_MOESM3_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM7_ESM.xlsx, sheet 7
• 43018_2022_474_MOESM10_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM2_ESM.xlsx, sheet 7
• 43018_2022_474_MOESM2_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM10_ESM.xlsx, sheet 7
• 43018_2022_474_MOESM3_ESM.xlsx, sheet 7

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs150036236

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.

Nature Communications

Shah, Jennifer B JB; Pueschl, Dana D; Wubbenhorst, Bradley B; Fan, Mengyao M; Pluta, John J; D'Andrea, Kurt K; Hubert, Anna P AP; Shilan, Jake S JS; Zhou, Wenting W; Kraya, Adam A AA; Llop Guevara, Alba A; Ruan, Catherine C; Serra, Violeta V; Balmaña, Judith J; Feldman, Michael M; Morin, Pat J PJ; Nayak, Anupma A; Maxwell, Kara N KN; Domchek, Susan M SM; Nathanson, Katherine L KL

Publication Date: 2022-11-07

Variant appearance in text: EGFR: R831H

PubMed Link: 36344544

Variant Present in the following documents:

• 41467_2022_34523_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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Non-small cell lung cancer in China.

Cancer Communications (London, England)

Chen, Peixin P; Liu, Yunhuan Y; Wen, Yaokai Y; Zhou, Caicun C

Publication Date: 2022-10

Variant appearance in text: EGFR: R831H

PubMed Link: 36075878

Variant Present in the following documents:

• Main text
• CAC2-42-937.pdf

View BVdb publication page

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High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer.

Nature Communications

Palafox, Marta M; Monserrat, Laia L; Bellet, Meritxell M; Villacampa, Guillermo G; Gonzalez-Perez, Abel A; Oliveira, Mafalda M; Brasó-Maristany, Fara F; Ibrahimi, Nusaibah N; Kannan, Srinivasaraghavan S; Mina, Leonardo L; Herrera-Abreu, Maria Teresa MT; Òdena, Andreu A; Sánchez-Guixé, Mònica M; Capelán, Marta M; Azaro, Analía A; Bruna, Alejandra A; Rodríguez, Olga O; Guzmán, Marta M; Grueso, Judit J; Viaplana, Cristina C; Hernández, Javier J; Su, Faye F; Lin, Kui K; Clarke, Robert B RB; Caldas, Carlos C; Arribas, Joaquín J; Michiels, Stefan S; García-Sanz, Alicia A; Turner, Nicholas C NC; Prat, Aleix A; Nuciforo, Paolo P; Dienstmann, Rodrigo R; Verma, Chandra S CS; Lopez-Bigas, Nuria N; Scaltriti, Maurizio M; Arnedos, Monica M; Saura, Cristina C; Serra, Violeta V

Publication Date: 2022-09-07

Variant appearance in text: EGFR: 2492G>A; R831H

PubMed Link: 36071033

Variant Present in the following documents:

• 41467_2022_32828_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2492G>A; R831H

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Mutational spectrum and prognosis in Chinese patients with prefibrotic primary myelofibrosis.

Ejhaem

Cheng, Chi-Keung CK; Lai, Jennifer W Y JWY; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Wong, Raymond S M RSM; Chan, Natalie P H NPH; Cheung, Joyce S JS; Luo, Xi X; Pitts, Herbert-Augustus HA; Ng, Margaret H L MHL

Publication Date: 2022-02

Variant appearance in text: EGFR: 2492G>A; R831H; rs150036236

PubMed Link: 35846205

Variant Present in the following documents:

• JHA2-3-184-s002.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: EGFR: R831H

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer

Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X

Publication Date: 2022-05-16

Variant appearance in text: EGFR: 2492G>A; R831H

PubMed Link: 35578198

Variant Present in the following documents:

• 12885_2022_9602_MOESM9_ESM.xlsx, sheet 1

View BVdb publication page

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Are transient protein-protein interactions more dispensable?

Plos Computational Biology

Ghadie, Mohamed Ali MA; Xia, Yu Y

Publication Date: 2022-04

Variant appearance in text: EGFR: 2492G>A; Arg831His

PubMed Link: 35404956

Variant Present in the following documents:

• pcbi.1010013.s002.xlsx, sheet 4

View BVdb publication page

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Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer

Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B

Publication Date: 2022-03-19

Variant appearance in text: EGFR: R831H

PubMed Link: 35305596

Variant Present in the following documents:

• Main text
• 12885_2022_Article_9409.pdf

View BVdb publication page

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Pedigree analysis of the EGFR p.V1010M germline mutation in a family with a family history of non-small-cell lung cancer.

Annals Of Translational Medicine

Li, Na N; Liu, Chunyi C; Xiong, Lan L; Huang, Depei D; Jiang, Youfan Y

Publication Date: 2022-02

Variant appearance in text: EGFR: R831H

PubMed Link: 35284553

Variant Present in the following documents:

• Main text
• atm-10-03-154.pdf

View BVdb publication page

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Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Frontiers In Oncology

Lin, Xinqing X; Peng, Muyun M; Chen, Quanfang Q; Yuan, Mingming M; Chen, Rongrong R; Deng, Haiyi H; Deng, Jiaxi J; Liu, Ouqi O; Weng, Yuqing Y; Chen, Mingjiu M; Zhou, Chengzhi C

Publication Date: 2021

Variant appearance in text: EGFR: R831H

PubMed Link: 34869019

Variant Present in the following documents:

• Main text
• fonc-11-774156.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: R831H

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Arg831His

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Arg831His

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Pathology Oncology Research : Por

Mao, Linlin L; Zhao, Weiwei W; Li, Xiaoxia X; Zhang, Shangfei S; Zhou, Changhong C; Zhou, Danyan D; Ou, Xiaohua X; Xu, Yanyan Y; Tang, Yuanxiao Y; Ou, Xiaoyong X; Hu, Changming C; Ding, Xiangdong X; Luo, Pifu P; Yu, Shihui S

Publication Date: 2021

Variant appearance in text: EGFR: R831H

PubMed Link: 34257561

Variant Present in the following documents:

• Main text
• pore-27-602726.pdf

View BVdb publication page

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Higher Mutation Burden in High Proliferation Compartments of Heterogeneous Melanoma Tumors.

International Journal Of Molecular Sciences

Grzywa, Tomasz M TM; Koppolu, Agnieszka A AA; Paskal, Wiktor W; Klicka, Klaudia K; Rydzanicz, Małgorzata M; Wejman, Jarosław J; Płoski, Rafał R; Włodarski, Paweł K PK

Publication Date: 2021-04-09

Variant appearance in text: EGFR: 2492G>A; Arg831His

PubMed Link: 33918692

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular profile of KRAS G12C-mutant colorectal and non-small-cell lung cancer.

Bmc Cancer

Araujo, Luiz Henrique LH; Souza, Bianca Mendes BM; Leite, Laura Rabelo LR; Parma, Sabrina A F SAF; Lopes, Natália P NP; Malta, Frederico S V FSV; Freire, Maíra C M MCM

Publication Date: 2021-02-25

Variant appearance in text: EGFR: R831H

PubMed Link: 33632153

Variant Present in the following documents:

• Main text
• 12885_2021_Article_7884.pdf

View BVdb publication page

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The Genomic Landscape of Actinic Keratosis.

The Journal Of Investigative Dermatology

Thomson, Jason J; Bewicke-Copley, Findlay F; Anene, Chinedu Anthony CA; Gulati, Abha A; Nagano, Ai A; Purdie, Karin K; Inman, Gareth J GJ; Proby, Charlotte M CM; Leigh, Irene M IM; Harwood, Catherine A CA; Wang, Jun J

Publication Date: 2021-07

Variant appearance in text: EGFR: 2492G>A; R831H; rs150036236

PubMed Link: 33482222

Variant Present in the following documents:

• mmc1.xlsx, sheet 4

View BVdb publication page

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BEBT-109, a pan-mutant-selective EGFR inhibitor with potent antitumor activity in EGFR-mutant non-small cell lung cancer.

Translational Oncology

Fan, Fushun F; Zhou, Minhua M; Ye, Xiaolan X; Mo, Zhenxian Z; Ma, Yaru Y; Luo, Liying L; Liang, Xiaotong X; Liu, Haiqi H; Weng, Yunwo Y; Lin, Mingsheng M; Liu, Xinjian X; Cai, Xiong X; Qian, Changgeng C

Publication Date: 2021-02

Variant appearance in text: EGFR: R831H

PubMed Link: 33321427

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Comprehensive genomic profiling for patients with chemotherapy-naïve advanced cancer.

Cancer Science

Kondo, Tomohiro T; Matsubara, Junichi J; Quy, Pham Nguyen PN; Fukuyama, Keita K; Nomura, Motoo M; Funakoshi, Taro T; Doi, Keitaro K; Sakamori, Yuichi Y; Yoshioka, Masahiro M; Yokoyama, Akira A; Tamaoki, Masashi M; Kou, Tadayuki T; Hirohashi, Kenshiro K; Yamada, Atsushi A; Yamamoto, Yoshihiro Y; Minamiguchi, Sachiko S; Nishigaki, Masakazu M; Yamada, Takahiro T; Kanai, Masashi M; Matsumoto, Shigemi S; Muto, Manabu M

Publication Date: 2021-01

Variant appearance in text: EGFR: R831H

PubMed Link: 33007138

Variant Present in the following documents:

• CAS-112-296-s002.xlsx, sheet 1

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: EGFR: R831H

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGFR: R831H

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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The contribution of hereditary cancer-related germline mutations to lung cancer susceptibility.

Translational Lung Cancer Research

Liu, Mengyuan M; Liu, Xinyi X; Suo, Peisu P; Gong, Yuan Y; Qu, Baolin B; Peng, Xiumei X; Xiao, Wenhua W; Li, Yuemin Y; Chen, Yan Y; Zeng, Zhen Z; Lu, Yinying Y; Huang, Tanxiao T; Zhao, Yingshen Y; Liu, Ming M; Li, Lifeng L; Chen, Yaru Y; Zhou, Yanqing Y; Liu, Guifeng G; Yao, Jianfei J; Chen, Shifu S; Song, Lele L

Publication Date: 2020-06

Variant appearance in text: EGFR: R831H

PubMed Link: 32676327

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: R831H

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11

View BVdb publication page

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Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan-cancer analysis.

Cancer Communications (London, England)

Liu, Haijing H; Zhang, Bo B; Sun, Zhifu Z

Publication Date: 2020-01

Variant appearance in text: EGFR: 2492G>A; R831H

PubMed Link: 32067422

Variant Present in the following documents:

• CAC2-40-43-s001.xlsx, sheet 1

View BVdb publication page

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Monitoring treatment efficacy and resistance in breast cancer patients via circulating tumor DNA genomic profiling.

Molecular Genetics & Genomic Medicine

Chen, Zhanhong Z; Sun, Tian T; Yang, Ziyan Z; Zheng, Yabing Y; Yu, Ruoying R; Wu, Xue X; Yan, Junrong J; Shao, Yang W YW; Shao, Xiying X; Cao, Wenming W; Wang, Xiaojia X

Publication Date: 2020-02

Variant appearance in text: EGFR: Arg831His

PubMed Link: 31867841

Variant Present in the following documents:

• Main text
• MGG3-8-e1079.pdf
• MGG3-8-e1079-s004.xlsx, sheet 1

View BVdb publication page

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Genomic profile of urine has high diagnostic sensitivity compared to cytology in non-invasive urothelial bladder cancer.

Cancer Science

Hirotsu, Yosuke Y; Yokoyama, Hitoshi H; Amemiya, Kenji K; Hagimoto, Takashi T; Daimon, Hironori H; Hosaka, Kyoko K; Oyama, Toshio T; Mochizuki, Hitoshi H; Omata, Masao M

Publication Date: 2019-10

Variant appearance in text: EGFR: R831H

PubMed Link: 31368627

Variant Present in the following documents:

• CAS-110-3235.pdf

View BVdb publication page

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Liquid biopsy-based comprehensive gene mutation profiling for gynecological cancer using CAncer Personalized Profiling by deep Sequencing.

Scientific Reports

Iwahashi, Naoyuki N; Sakai, Kazuko K; Noguchi, Tomoko T; Yahata, Tamaki T; Matsukawa, Hitomi H; Toujima, Saori S; Nishio, Kazuto K; Ino, Kazuhiko K

Publication Date: 2019-07-18

Variant appearance in text: EGFR: R831H

PubMed Link: 31320709

Variant Present in the following documents:

• Main text
• 41598_2019_Article_47030.pdf

View BVdb publication page

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Analysis of cell-free circulating tumor DNA in 419 patients with glioblastoma and other primary brain tumors.

Cns Oncology

Piccioni, David E DE; Achrol, Achal Singh AS; Kiedrowski, Lesli A LA; Banks, Kimberly C KC; Boucher, Najee N; Barkhoudarian, Garni G; Kelly, Daniel F DF; Juarez, Tiffany T; Lanman, Richard B RB; Raymond, Victoria M VM; Nguyen, Minhdan M; Truong, Judy D JD; Heng, Annie A; Gill, Jaya J; Saria, Marlon M; Pingle, Sandeep C SC; Kesari, Santosh S

Publication Date: 2019-06

Variant appearance in text: EGFR: R831H

PubMed Link: 30855176

Variant Present in the following documents:

• Main text
• cns-08-34.pdf

View BVdb publication page

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Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

The Journal Of Molecular Diagnostics : Jmd

Clark, Travis A TA; Chung, Jon H JH; Kennedy, Mark M; Hughes, Jason D JD; Chennagiri, Niru N; Lieber, Daniel S DS; Fendler, Bernard B; Young, Lauren L; Zhao, Mandy M; Coyne, Michael M; Breese, Virginia V; Young, Geneva G; Donahue, Amy A; Pavlick, Dean D; Tsiros, Alyssa A; Brennan, Timothy T; Zhong, Shan S; Mughal, Tariq T; Bailey, Mark M; He, Jie J; Roels, Steven S; Frampton, Garrett M GM; Spoerke, Jill M JM; Gendreau, Steven S; Lackner, Mark M; Schleifman, Erica E; Peters, Eric E; Ross, Jeffrey S JS; Ali, Siraj M SM; Miller, Vincent A VA; Gregg, Jeffrey P JP; Stephens, Philip J PJ; Welsh, Allison A; Otto, Geoff A GA; Lipson, Doron D

Publication Date: 2018-09

Variant appearance in text: EGFR: R831H

PubMed Link: 29936259

Variant Present in the following documents:

• mmc12.xlsx, sheet 1

View BVdb publication page

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Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling.

Oncotarget

Tarlock, Katherine K; Zhong, Shan S; He, Yuting Y; Ries, Rhonda R; Severson, Eric E; Bailey, Mark M; Morley, Samantha S; Balasubramanian, Sohail S; Erlich, Rachel R; Lipson, Doron D; Otto, Geoff A GA; Vergillo, Jo-Anne JA; Kolb, E Anders EA; Ross, Jeffrey S JS; Mughal, Tariq T; Stephens, Philip J PJ; Miller, Vincent V; Meshinchi, Soheil S; He, Jie J

Publication Date: 2018-05-29

Variant appearance in text: EGFR: 2492G>A; R831H

PubMed Link: 29899868

Variant Present in the following documents:

• oncotarget-09-26417-s005.xlsx, sheet 1

View BVdb publication page

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A Phase II Study of Pelareorep (REOLYSIN®) in Combination with Gemcitabine for Patients with Advanced Pancreatic Adenocarcinoma.

Cancers

Mahalingam, Devalingam D; Goel, Sanjay S; Aparo, Santiago S; Patel Arora, Sukeshi S; Noronha, Nicole N; Tran, Hue H; Chakrabarty, Romit R; Selvaggi, Giovanni G; Gutierrez, Andres A; Coffey, Matthew M; Nawrocki, Steffan T ST; Nuovo, Gerard G; Mita, Monica M MM

Publication Date: 2018-05-25

Variant appearance in text: EGFR: R831H

PubMed Link: 29799479

Variant Present in the following documents:

• cancers-10-00160-s001.pdf

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: R831H

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 1

View BVdb publication page

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Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

The Journal Of Pathology

Temko, Daniel D; Van Gool, Inge C IC; Rayner, Emily E; Glaire, Mark M; Makino, Seiko S; Brown, Matthew M; Chegwidden, Laura L; Palles, Claire C; Depreeuw, Jeroen J; Beggs, Andrew A; Stathopoulou, Chaido C; Mason, John J; Baker, Ann-Marie AM; Williams, Marc M; Cerundolo, Vincenzo V; Rei, Margarida M; Taylor, Jenny C JC; Schuh, Anna A; Ahmed, Ahmed A; Amant, Frédéric F; Lambrechts, Diether D; Smit, Vincent Thbm VT; Bosse, Tjalling T; Graham, Trevor A TA; Church, David N DN; Tomlinson, Ian I

Publication Date: 2018-07

Variant appearance in text: EGFR: 2492G>A; R831H

PubMed Link: 29604063

Variant Present in the following documents:

• PATH-245-283-s022.xlsx, sheet 1

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Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors.

Erj Open Research

Wu, Shang-Gin SG; Chang, Yih-Leong YL; Yu, Chong-Jen CJ; Yang, Pan-Chyr PC; Shih, Jin-Yuan JY

Publication Date: 2017-07

Variant appearance in text: EGFR: R831H

PubMed Link: 28717642

Variant Present in the following documents:

• Main text
• 00092-2016.pdf

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: EGFR: R831H; rs150036236

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamics.

Proteome Science

Ma, Lichun L; Zou, Bin B; Yan, Hong H

Publication Date: 2016

Variant appearance in text: EGFR: R831H

PubMed Link: 27610045

Variant Present in the following documents:

• Main text
• 12953_2016_Article_102.pdf

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Protein-structure-guided discovery of functional mutations across 19 cancer types.

Nature Genetics

Niu, Beifang B; Scott, Adam D AD; Sengupta, Sohini S; Bailey, Matthew H MH; Batra, Prag P; Ning, Jie J; Wyczalkowski, Matthew A MA; Liang, Wen-Wei WW; Zhang, Qunyuan Q; McLellan, Michael D MD; Sun, Sam Q SQ; Tripathi, Piyush P; Lou, Carolyn C; Ye, Kai K; Mashl, R Jay RJ; Wallis, John J; Wendl, Michael C MC; Chen, Feng F; Ding, Li L

Publication Date: 2016-08

Variant appearance in text: EGFR: Arg831His

PubMed Link: 27294619

Variant Present in the following documents:

• Main text

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Use of dedicated gene panel sequencing using next generation sequencing to improve the personalized care of lung cancer.

Oncotarget

Kaderbhai, Coureche Guillaume CG; Boidot, Romain R; Beltjens, Françoise F; Chevrier, Sandy S; Arnould, Laurent L; Favier, Laure L; Lagrange, Aurélie A; Coudert, Bruno B; Ghiringhelli, François F

Publication Date: 2016-04-26

Variant appearance in text: EGFR: R831H

PubMed Link: 27027238

Variant Present in the following documents:

• oncotarget-07-24860.pdf
• oncotarget-07-24860-s001.pdf

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